EC 2.7.1.1: Hexokinase
Reaction catalysed:
ATP + D-hexose = ADP + D-hexose 6-phosphate
Systematic name:
ATP:D-hexose 6-phosphotransferase
Alternative Name(s):
- ATP-dependent hexokinase
- Glucose ATP phosphotransferase
- Hexokinase (phosphorylating)
- Hexokinase D
- Hexokinase type I
- Hexokinase type II
- Hexokinase type III
- Hexokinase type IV
- Hexokinase type IV (glucokinase)
- Hexokinase type IV glucokinase
GO terms
Biochemical function:
Biological process:
- negative regulation of apoptotic signaling pathway
- fructose import across plasma membrane
- glucose 6-phosphate metabolic process
- carbohydrate phosphorylation
- D-glucose import
- regulation of transcription by glucose
- hexose metabolic process
- phosphorylation
- regulation of cell size
- glycolytic process
- mannose metabolic process
- glucose metabolic process
- fructose metabolic process
- carbohydrate metabolic process
- intracellular glucose homeostasis
Cellular component:
Sequence families
Protein families (Pfam)
InterPro annotationsStructure domains
CATH domains
3.40.367.20
Class:
Alpha Beta
Architecture:
3-Layer(aba) Sandwich
Topology:
Hexokinase; domain 1
Homology:
Hexokinase; domain 1
Occurring in:
3.30.420.40
Class:
Alpha Beta
Architecture:
2-Layer Sandwich
Topology:
Nucleotidyltransferase; domain 5
Homology:
Nucleotidyltransferase; domain 5
Occurring in:
SCOP annotation