Assemblies
Assembly Name:
DNA ligase IV complex
Multimeric state:
hetero trimer
Accessible surface area:
24937.98 Å2
Buried surface area:
7367.21 Å2
Dissociation area:
997
Å2
Dissociation energy (ΔGdiss):
8.66
kcal/mol
Dissociation entropy (TΔSdiss):
9.63
kcal/mol
Symmetry number:
1
PDBe Complex ID:
PDB-CPX-156092
Macromolecules
Chains: A, B
Length: 213 amino acids
Theoretical weight: 24.47 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Pfam:
InterPro:
Length: 213 amino acids
Theoretical weight: 24.47 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
Q13426 (Residues: 1-213; Coverage: 63%)
Pfam:
InterPro:
- XRCC4, N-terminal domain superfamily
- DNA repair protein XRCC4
- XRCC4-like, N-terminal domain superfamily
- DNA repair protein XRCC4-like, C-terminal
- DNA double-strand break repair and VJ recombination XRCC4, N-terminal
- Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Chain: C
Length: 37 amino acids
Theoretical weight: 4.32 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Pfam: DNA ligase IV
InterPro: DNA ligase IV domain
Length: 37 amino acids
Theoretical weight: 4.32 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical: P49917 (Residues: 748-784; Coverage: 4%)
Pfam: DNA ligase IV
InterPro: DNA ligase IV domain
