› 1imt

Solution NMR

MAMBA INTESTINAL TOXIN 1, NMR, 39 STRUCTURES

Released:
DOI: 10.2210/pdb1imt/pdb
PDB entry 1imt coloured by chain, ensemble of 39 models, front view.
PDB entry 1imt coloured by chain, ensemble of 39 models, side view.
PDB entry 1imt coloured by chain, ensemble of 39 models, top view.
Source organism: Dendroaspis polylepis polylepis
Primary publication:
A structural homologue of colipase in black mamba venom revealed by NMR floating disulphide bridge analysis.
Boisbouvier J, Albrand JP, Blackledge M, Jaquinod M, Schweitz H, Lazdunski M, Marion D
J Mol Biol 283 205-19 (1998)
PMID: 9761684

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-150556 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Toxin MIT1 Chain: A
Molecule details ›
Chain: A
Length: 80 amino acids
Theoretical weight: 8.53 KDa
Source organism: Dendroaspis polylepis polylepis
UniProt:
  • Canonical: P25687 (Residues: 1-80; Coverage: 99%)
Sequence domains: Prokineticin
Structure domains: Lipase, subunit A

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: RESTRAINED SIMULATED ANNEALING AND RESTRAINED MOLECULAR DYNAMICS ENERGY REFINEMENT

Quick links

Citations

18 review citations

Function and biological roles of the Dickkopf family of Wnt modulators.
Niehrs C. (2006)
17 more

4 mentions without citation

The role of the prokineticin 2 pathway in human reproduction: evidence from the study of human and murine gene mutations.
Martin et al. (2011)
3 more