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INTERFERON ALPHA-2A, NMR, 24 STRUCTURES

Solution NMR
PDB entry 1itf coloured by chain, ensemble of 24 models, front view.
PDB entry 1itf coloured by chain, ensemble of 24 models, side view.
PDB entry 1itf coloured by chain, ensemble of 24 models, top view.
Source organism: Homo sapiens
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Interferon alpha-2
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Multimeric state: monomeric
Accessible surface area: 9376.45 Å2
Buried surface area: 0.0 Å2
Dissociation area: 0 Å2
Dissociation energy (ΔGdiss): 0 kcal/mol
Dissociation entropy (TΔSdiss): 0 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-134391

Macromolecules

Interferon alpha-2
Chain: A
Length: 165 amino acids
Theoretical weight: 19.26 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P01563 (Residues: 24-188; Coverage: 100%)
Gene names: IFNA2, IFNA2A, IFNA2B, IFNA2C
Pfam: Interferon alpha/beta domain
InterPro:
CATH: Growth Hormone; Chain: A;
SCOP: Interferons/interleukin-10 (IL-10)
Interferon alpha-2 in PDB entry 1itf, assembly 1, front view.
Interferon alpha-2 in PDB entry 1itf, assembly 1, side view.
Interferon alpha-2 in PDB entry 1itf, assembly 1, top view.
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