Function and Biology Details
Reaction catalysed:
(R)-lactate + NAD(+) = pyruvate + NADH
Sequence domains:
- D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site
- D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1
- D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain
- NAD(P)-binding domain superfamily
- D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
Structure analysis Details
Assembly composition:
homo dimer (preferred)
Assembly name:
D-lactate dehydrogenase (preferred)
PDBe Complex ID:
PDB-CPX-150689 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
D-lactate dehydrogenase
Molecule details ›
Chains: A, B, C, D
Length: 333 amino acids
Theoretical weight: 37.11 KDa
Source organism: Lactobacillus delbrueckii subsp. bulgaricus
Expression system: Escherichia coli
UniProt:
Sequence domains:
Length: 333 amino acids
Theoretical weight: 37.11 KDa
Source organism: Lactobacillus delbrueckii subsp. bulgaricus
Expression system: Escherichia coli
UniProt:
- Canonical:
P26297 (Residues: 1-333; Coverage: 100%)
Sequence domains:
- D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
- D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
