Function and Biology

Crystal Structure of the DNA-Binding Domain Zalpha of DLM-1 Bound to Z-DNA

Source organism: Mus musculus
Biochemical function: double-stranded RNA adenosine deaminase activity
Biological process: positive regulation of type I interferon-mediated signaling pathway
Cellular component: not assigned

Sequence family

Pfam Protein family (Pfam)
PF02295
Domain description: Adenosine deaminase z-alpha domain
Occurring in:
  1. Z-DNA-binding protein 1
The deposited structure of PDB entry 1j75 contains 1 copy of Pfam domain PF02295 (Adenosine deaminase z-alpha domain) in Z-DNA-binding protein 1. Showing 1 copy in chain B [auth A].

InterPro InterPro annotations
IPR042371
Domain description: Z-binding domain
Occurring in:
  1. Z-DNA-binding protein 1
IPR036390
Domain description: Winged helix DNA-binding domain superfamily
Occurring in:
  1. Z-DNA-binding protein 1
IPR042361
Domain description: Z-DNA-binding protein 1
Occurring in:
  1. Z-DNA-binding protein 1
IPR036388
Domain description: Winged helix-like DNA-binding domain superfamily
Occurring in:
  1. Z-DNA-binding protein 1

Structure domain

CATH CATH domain
1.10.10.10
Class: Mainly Alpha
Architecture: Orthogonal Bundle
Topology: Arc Repressor Mutant, subunit A
Homology: Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
Occurring in:
  1. Z-DNA-binding protein 1
The deposited structure of PDB entry 1j75 contains 1 copy of CATH domain 1.10.10.10 (Arc Repressor Mutant, subunit A) in Z-DNA-binding protein 1. Showing 1 copy in chain B [auth A].
SCOP SCOP annotation
46853
Class: All alpha proteins
Fold: DNA/RNA-binding 3-helical bundle
Superfamily: "Winged helix" DNA-binding domain
Occurring in:
  1. Z-DNA-binding protein 1
The deposited structure of PDB entry 1j75 contains 1 copy of SCOP domain 46853 (Z-DNA binding domain) in Z-DNA-binding protein 1. Showing 1 copy in chain B [auth A].