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HUMAN INTERLEUKIN 3 (IL-3) MUTANT WITH TRUNCATION AT BOTH N-AND C-TERMINI AND 14 RESIDUE CHANGES, NMR, MINIMIZED AVERAGE STRUCTURE

Source organism: Homo sapiens
Biochemical function: growth factor activity
Biological process: immune response
Cellular component: extracellular region

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GO terms

Biochemical function:
Biological process:
Cellular component:

Sequence family

Pfam Protein family (Pfam)
PF02059
Domain description: Interleukin-3
Occurring in:
  1. Interleukin-3
The deposited structure of PDB entry 1jli contains 1 copy of Pfam domain PF02059 (Interleukin-3) in Interleukin-3. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR002183
Domain description: Interleukin-3
Occurring in:
  1. Interleukin-3
IPR009079
Domain description: Four-helical cytokine-like, core
Occurring in:
  1. Interleukin-3

Structure domain

CATH CATH domain
1.20.1250.10
Class: Mainly Alpha
Architecture: Up-down Bundle
Topology: Growth Hormone; Chain: A;
Homology: Growth Hormone; Chain: A;
Occurring in:
  1. Interleukin-3
The deposited structure of PDB entry 1jli contains 1 copy of CATH domain 1.20.1250.10 (Growth Hormone; Chain: A;) in Interleukin-3. Showing 1 copy in chain A.
SCOP SCOP annotation
47286
Class: All alpha proteins
Fold: 4-helical cytokines
Superfamily: 4-helical cytokines
Occurring in:
  1. Interleukin-3
The deposited structure of PDB entry 1jli contains 1 copy of SCOP domain 47286 (Short-chain cytokines) in Interleukin-3. Showing 1 copy in chain A.

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