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Crystal Structure of Fab-Estradiol Complexes

Source organism: Mus musculus
Biochemical function: antigen binding
Biological process: immunoglobulin mediated immune response
Cellular component: IgG immunoglobulin complex

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GO terms

Biochemical function:
Biological process:
Cellular component:

Sequence family

Pfam Protein family (Pfam)
PF07654
Domain description: Immunoglobulin C1-set domain
Occurring in:
  1. Ig lambda-1 chain C region
The deposited structure of PDB entry 1jnh contains 4 copies of Pfam domain PF07654 (Immunoglobulin C1-set domain) in Ig lambda-1 chain C region. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR003597
Domain description: Immunoglobulin C1-set
Occurring in:
  1. Ig lambda-1 chain C region
  2. monoclonal anti-estradiol 10G6D6 Fab heavy chain
IPR013106
Domain description: Immunoglobulin V-set domain
Occurring in:
  1. Ig lambda-1 chain C region
  2. monoclonal anti-estradiol 10G6D6 Fab heavy chain
IPR036179
Domain description: Immunoglobulin-like domain superfamily
Occurring in:
  1. Ig lambda-1 chain C region
  2. monoclonal anti-estradiol 10G6D6 Fab heavy chain
IPR013783
Domain description: Immunoglobulin-like fold
Occurring in:
  1. Ig lambda-1 chain C region
  2. monoclonal anti-estradiol 10G6D6 Fab heavy chain
IPR007110
Domain description: Immunoglobulin-like domain
Occurring in:
  1. Ig lambda-1 chain C region
  2. monoclonal anti-estradiol 10G6D6 Fab heavy chain
IPR003599
Domain description: Immunoglobulin domain subtype
Occurring in:
  1. Ig lambda-1 chain C region
  2. monoclonal anti-estradiol 10G6D6 Fab heavy chain
IPR003006
Domain description: Immunoglobulin/major histocompatibility complex, conserved site
Occurring in:
  1. Ig lambda-1 chain C region

Structure domain

CATH CATH domain
2.60.40.10
Class: Mainly Beta
Architecture: Sandwich
Topology: Immunoglobulin-like
Homology: Immunoglobulins
Occurring in:
  1. Ig lambda-1 chain C region
  2. monoclonal anti-estradiol 10G6D6 Fab heavy chain
The deposited structure of PDB entry 1jnh contains 8 copies of CATH domain 2.60.40.10 (Immunoglobulin-like) in Ig lambda-1 chain C region. Showing 2 copies in chain A.
The deposited structure of PDB entry 1jnh contains 8 copies of CATH domain 2.60.40.10 (Immunoglobulin-like) in monoclonal anti-estradiol 10G6D6 Fab heavy chain. Showing 2 copies in chain B.
SCOP SCOP annotations
48942
Class: All beta proteins
Fold: Immunoglobulin-like beta-sandwich
Superfamily: Immunoglobulin
Occurring in:
  1. Ig lambda-1 chain C region
  2. monoclonal anti-estradiol 10G6D6 Fab heavy chain
The deposited structure of PDB entry 1jnh contains 4 copies of SCOP domain 48942 (C1 set domains (antibody constant domain-like)) in Ig lambda-1 chain C region. Showing 1 copy in chain A.
The deposited structure of PDB entry 1jnh contains 4 copies of SCOP domain 48942 (C1 set domains (antibody constant domain-like)) in monoclonal anti-estradiol 10G6D6 Fab heavy chain. Showing 1 copy in chain B.
48727
Class: All beta proteins
Fold: Immunoglobulin-like beta-sandwich
Superfamily: Immunoglobulin
Occurring in:
  1. Ig lambda-1 chain C region
  2. monoclonal anti-estradiol 10G6D6 Fab heavy chain
The deposited structure of PDB entry 1jnh contains 4 copies of SCOP domain 48727 (V set domains (antibody variable domain-like)) in Ig lambda-1 chain C region. Showing 1 copy in chain A.
The deposited structure of PDB entry 1jnh contains 4 copies of SCOP domain 48727 (V set domains (antibody variable domain-like)) in monoclonal anti-estradiol 10G6D6 Fab heavy chain. Showing 1 copy in chain B.

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