› 1jpc

X-ray diffraction
2Å resolution

MANNOSE-SPECIFIC AGGLUTININ (LECTIN) FROM SNOWDROP (GALANTHUS NIVALIS) BULBS IN COMPLEX WITH MANNOSE-ALPHA1,6-(MANNOSE-ALPHA1,3)-MANNOSE-ALPHA1,6-(MANNOSE-ALPHA1,3)-MANNOSE

Released:
DOI: 10.2210/pdb1jpc/pdb
PDB entry 1jpc coloured by chain, front view.
PDB entry 1jpc coloured by chain, side view.
PDB entry 1jpc coloured by chain, top view.
Source organism: Galanthus nivalis
Primary publication:
The 2.0 A structure of a cross-linked complex between snowdrop lectin and a branched mannopentaose: evidence for two unique binding modes.
Wright CS, Hester G
Structure 4 1339-52 (1996)
PMID: 8939757

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-542218 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (3 distinct):
Mannose-specific lectin Chain: A
Molecule details ›
Chain: A
Length: 109 amino acids
Theoretical weight: 12.06 KDa
Source organism: Galanthus nivalis
UniProt:
  • Canonical: P30617 (Residues: 24-132; Coverage: 79%)
Structure domains: Bulb-type lectin domain

Ligands and Environments

Carbohydrate polymer : NEW Components: MAN
Carbohydrate polymer
Carbohydrate polymer : NEW Components: MAN
Carbohydrate polymer
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: I4122
Unit cell:
a: 96.339Å b: 96.339Å c: 68.635Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.187 0.187 0.22

Quick links

Citations

8 review citations

Lectins.
Vijayan et al. (1999)
7 more

10 mentions without citation

Structure-function and application of plant lectins in disease biology and immunity.
Mishra et al. (2019)
9 more