Function and Biology

Structural Basis for the Interaction of Antibiotics with the Peptidyl Transferase Center in Eubacteria

Source organism: Deinococcus radiodurans
Biochemical function: rRNA binding
Biological process: translation
Cellular component: ribonucleoprotein complex

GO terms

Biochemical function:
Biological process:
Cellular component:

Sequence families

Pfam Protein families (Pfam)
PF01783
Domain description: Ribosomal L32p protein family
Occurring in:
  1. Large ribosomal subunit protein bL32
The deposited structure of PDB entry 1k01 contains 1 copy of Pfam domain PF01783 (Ribosomal L32p protein family) in Large ribosomal subunit protein bL32. Showing 1 copy in chain D [auth M].

PF00237
Domain description: Ribosomal protein L22p/L17e
Occurring in:
  1. Large ribosomal subunit protein uL22
The deposited structure of PDB entry 1k01 contains 1 copy of Pfam domain PF00237 (Ribosomal protein L22p/L17e) in Large ribosomal subunit protein uL22. Showing 1 copy in chain C [auth L].

PF00573
Domain description: Ribosomal protein L4/L1 family
Occurring in:
  1. Large ribosomal subunit protein uL4
The deposited structure of PDB entry 1k01 contains 1 copy of Pfam domain PF00573 (Ribosomal protein L4/L1 family) in Large ribosomal subunit protein uL4. Showing 1 copy in chain B [auth K].

Rfam RNA family (Rfam)
RF02541
Domain description: Bacterial large subunit ribosomal RNA
Occurring in:
  1. 23S ribosomal RNA
The deposited structure of PDB entry 1k01 contains 1 copy of Rfam domain RF02541 (Bacterial large subunit ribosomal RNA) in 23S ribosomal RNA. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR002677
Domain description: Large ribosomal subunit protein bL32
Occurring in:
  1. Large ribosomal subunit protein bL32
IPR013005
Domain description: Large ribosomal subunit protein uL4-like
Occurring in:
  1. Large ribosomal subunit protein uL4
IPR001063
Domain description: Large ribosomal subunit protein uL22
Occurring in:
  1. Large ribosomal subunit protein uL22
IPR005727
Domain description: Large ribosomal subunit protein uL22, bacterial/chloroplast-type
Occurring in:
  1. Large ribosomal subunit protein uL22
IPR036394
Domain description: Ribosomal protein uL22 superfamily
Occurring in:
  1. Large ribosomal subunit protein uL22
IPR023574
Domain description: Large ribosomal subunit protein uL4 domain superfamily
Occurring in:
  1. Large ribosomal subunit protein uL4
IPR044957
Domain description: Large ribosomal subunit protein bL32, bacterial type
Occurring in:
  1. Large ribosomal subunit protein bL32
IPR011332
Domain description: Zinc-binding ribosomal protein
Occurring in:
  1. Large ribosomal subunit protein bL32
IPR018260
Domain description: Large ribosomal subunit protein uL22, conserved site
Occurring in:
  1. Large ribosomal subunit protein uL22
IPR047867
Domain description: Large ribosomal subunit protein uL22, bacterial/organelle-type
Occurring in:
  1. Large ribosomal subunit protein uL22
IPR002136
Domain description: Large ribosomal subunit protein uL4
Occurring in:
  1. Large ribosomal subunit protein uL4

Structure domain

SCOP SCOP annotation
58124
Class: Low resolution protein structures
Fold: Ribosome and ribosomal fragments
Superfamily: Ribosome and ribosomal fragments
Occurring in:
  1. Large ribosomal subunit protein uL4
  2. Large ribosomal subunit protein uL22
  3. Large ribosomal subunit protein bL32
The deposited structure of PDB entry 1k01 contains 1 copy of SCOP domain 58124 (Large subunit) in Large ribosomal subunit protein uL4. Showing 1 copy in chain B [auth K].
The deposited structure of PDB entry 1k01 contains 1 copy of SCOP domain 58124 (Large subunit) in Large ribosomal subunit protein uL22. Showing 1 copy in chain C [auth L].
The deposited structure of PDB entry 1k01 contains 1 copy of SCOP domain 58124 (Large subunit) in Large ribosomal subunit protein bL32. Showing 1 copy in chain D [auth M].