› 1kco

Solution NMR

Structure of e131 Zeta Peptide, a Potent Antagonist of the High-Affinity IgE Receptor

Released:
DOI: 10.2210/pdb1kco/pdb
PDB entry 1kco coloured by chain, ensemble of 20 models, front view.
PDB entry 1kco coloured by chain, ensemble of 20 models, side view.
PDB entry 1kco coloured by chain, ensemble of 20 models, top view.
Source organism: Synthetic construct
Primary publication:
Stable "zeta" peptides that act as potent antagonists of the high-affinity IgE receptor.
Nakamura GR, Reynolds ME, Chen YM, Starovasnik MA, Lowman HB
Proc Natl Acad Sci U S A 99 1303-8 (2002)
PMID: 11830661

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-162278 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
e131 Zeta Peptide Chain: A
Molecule details ›
Chain: A
Length: 22 amino acids
Theoretical weight: 2.54 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: hybrid distance geometry/simulated annealing, then further refined by restrained molecular dynamics
Expression system: Not provided

Quick links

Citations

10 review citations

IgE and mast cells in allergic disease.
Galli et al. (2012)
9 more

1 mention without citation

Stable "zeta" peptides that act as potent antagonists of the high-affinity IgE receptor.
Nakamura et al. (2002)