Function and Biology

Crystal Structure of a Taiwan Habu Venom Metalloproteinase complexed with pEQW.

Source organism: Protobothrops mucrosquamatus
Biochemical function: metallopeptidase activity
Biological process: proteolysis
Cellular component: not assigned

GO terms

Biochemical function:
Biological process:
Cellular component:
  • not assigned

Sequence family

Pfam Protein family (Pfam)
PF01421
Domain description: Reprolysin (M12B) family zinc metalloprotease
Occurring in:
  1. Snake venom metalloproteinase TM-3
The deposited structure of PDB entry 1kui contains 1 copy of Pfam domain PF01421 (Reprolysin (M12B) family zinc metalloprotease) in Snake venom metalloproteinase TM-3. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR034027
Domain description: Reprolysin domain, adamalysin-type
Occurring in:
  1. Snake venom metalloproteinase TM-3
IPR001590
Domain description: Peptidase M12B, ADAM/reprolysin
Occurring in:
  1. Snake venom metalloproteinase TM-3
IPR024079
Domain description: Metallopeptidase, catalytic domain superfamily
Occurring in:
  1. Snake venom metalloproteinase TM-3

Structure domain

CATH CATH domain
3.40.390.10
Class: Alpha Beta
Architecture: 3-Layer(aba) Sandwich
Topology: Collagenase (Catalytic Domain)
Homology: Collagenase (Catalytic Domain)
Occurring in:
  1. Snake venom metalloproteinase TM-3
The deposited structure of PDB entry 1kui contains 1 copy of CATH domain 3.40.390.10 (Collagenase (Catalytic Domain)) in Snake venom metalloproteinase TM-3. Showing 1 copy in chain A.
SCOP SCOP annotation
55519
Class: Alpha and beta proteins (a+b)
Fold: Zincin-like
Superfamily: Metalloproteases ("zincins"), catalytic domain
Occurring in:
  1. Snake venom metalloproteinase TM-3
The deposited structure of PDB entry 1kui contains 1 copy of SCOP domain 55519 (Reprolysin-like) in Snake venom metalloproteinase TM-3. Showing 1 copy in chain A.