› 1kwv

X-ray diffraction
2Å resolution

Rat mannose binding protein A complexed with a-Me-GlcNAc

Released:
DOI: 10.2210/pdb1kwv/pdb
PDB entry 1kwv coloured by chain, front view.
PDB entry 1kwv coloured by chain, side view.
PDB entry 1kwv coloured by chain, top view.
Source organism: Rattus norvegicus
Primary publication:
Orientation of bound ligands in mannose-binding proteins. Implications for multivalent ligand recognition.
Ng KK, Kolatkar AR, Park-Snyder S, Feinberg H, Clark DA, Drickamer K, Weis WI
J Biol Chem 277 16088-95 (2002)
PMID: 11850428

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-148817 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Mannose-binding protein A Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 149 amino acids
Theoretical weight: 16.48 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli
UniProt:
  • Canonical: P19999 (Residues: 90-238; Coverage: 67%)
Gene name: Mbl1
Sequence domains: Lectin C-type domain
Structure domains: Mannose-Binding Protein A, subunit A

Ligands and Environments

3 bound ligands:
Ligand NAG 3 x NAG
Ligand CA 9 x CA
Ligand CL 3 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: C2
Unit cell:
a: 79Å b: 85.29Å c: 98.33Å
α: 90° β: 105.6° γ: 90°
R-values:
R R work R free
0.212 0.212 0.249
Expression system: Escherichia coli

Quick links

Citations

15 review citations

The C-type lectin-like domain superfamily.
Zelensky et al. (2005)
14 more