› 1l0q

X-ray diffraction
2.4Å resolution

Tandem YVTN beta-propeller and PKD domains from an archaeal surface layer protein

Released:
DOI: 10.2210/pdb1l0q/pdb
PDB entry 1l0q coloured by chain, front view.
PDB entry 1l0q coloured by chain, side view.
PDB entry 1l0q coloured by chain, top view.
Source organism: Methanosarcina mazei S-6
Primary publication:
Archaeal surface layer proteins contain beta propeller, PKD, and beta helix domains and are related to metazoan cell surface proteins.
Jing H, Takagi J, Liu JH, Lindgren S, Zhang RG, Joachimiak A, Wang JH, Springer TA
Structure 10 1453-64 (2002)
PMID: 12377130

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-175871 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
PKD domain-containing protein Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 391 amino acids
Theoretical weight: 40.8 KDa
Source organism: Methanosarcina mazei S-6
Expression system: Escherichia coli
UniProt:
  • Canonical: Q50245 (Residues: 43-433; Coverage: 80%)
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands
2 modified residues:
Ligand MSE 20 x MSE
Ligand YCM 4 x YCM

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: C2
Unit cell:
a: 188.181Å b: 65.885Å c: 140.03Å
α: 90° β: 124.25° γ: 90°
R-values:
R R work R free
0.217 0.214 0.263
Expression system: Escherichia coli

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Citations

10 review citations

Protein arginine methyltransferases: evolution and assessment of their pharmacological and therapeutic potential.
Krause et al. (2007)
9 more

16 mentions without citation

Cholera- and anthrax-like toxins are among several new ADP-ribosyltransferases.
Fieldhouse et al. (2010)
15 more