1lpp

X-ray diffraction
2.18Å resolution

ANALOGS OF REACTION INTERMEDIATES IDENTIFY A UNIQUE SUBSTRATE BINDING SITE IN CANDIDA RUGOSA LIPASE

Released:

Function and Biology Details

Reaction catalysed:
Triacylglycerol + H(2)O = diacylglycerol + a carboxylate
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Assembly name:
PDBe Complex ID:
PDB-CPX-539436 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Lipase 1 Chain: A
Molecule details ›
Chain: A
Length: 549 amino acids
Theoretical weight: 58.59 KDa
Source organism: Diutina rugosa
Expression system: Not provided
UniProt:
  • Canonical: P20261 (Residues: 1-549; Coverage: 100%)
Gene name: LIP1
Sequence domains: Carboxylesterase family
Structure domains: alpha/beta hydrolase

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: C2221
Unit cell:
a: 65.1Å b: 97.4Å c: 176.2Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.137 0.137 not available
Expression system: Not provided