› 1lvr

Solution NMR

IC3 of CB1 (L431A,A432L) Bound to G(alpha)i

Released:
DOI: 10.2210/pdb1lvr/pdb
PDB entry 1lvr coloured by chain, front view.
PDB entry 1lvr coloured by chain, side view.
PDB entry 1lvr coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Cannabinoid receptor-G protein interactions: G(alphai1)-bound structures of IC3 and a mutant with altered G protein specificity.
Ulfers AL, McMurry JL, Miller A, Wang L, Kendall DA, Mierke DF
Protein Sci 11 2526-31 (2002)
PMID: 12237474

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-149293 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cannabinoid receptor 1 Chain: A
Molecule details ›
Chain: A
Length: 9 amino acids
Theoretical weight: 1.03 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P21554 (Residues: 338-346; Coverage: 2%)
Gene names: CNR, CNR1

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: metric matrix distance geometry to generate initial ensemble of structures; 20 lowest penalty structures used for ensemble-based IRMA refinement
Expression system: Not provided

Quick links

Citations

6 review citations

CB(1) cannabinoid receptors and their associated proteins.
Howlett et al. (2010)
5 more

1 mention without citation

Cannabinoid receptor-G protein interactions: G(alphai1)-bound structures of IC3 and a mutant with altered G protein specificity.
Ulfers et al. (2002)