› › Function and Biology

Crystal Structure of the coiled coil region 129-250 of the tumor suppressor gene product APC

Source organism: Homo sapiens
Biochemical function: beta-catenin binding
Biological process: negative regulation of Wnt signaling pathway
Cellular component: not assigned

Quick links

GO terms

Biochemical function:
Biological process:
Cellular component:
  • not assigned

Sequence family

Pfam Protein family (Pfam)
PF11414
Domain description: Adenomatous polyposis coli tumour suppressor protein
Occurring in:
  1. Adenomatous polyposis coli protein
The deposited structure of PDB entry 1m5i contains 1 copy of Pfam domain PF11414 (Adenomatous polyposis coli tumour suppressor protein) in Adenomatous polyposis coli protein. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR026831
Domain description: Adenomatous polyposis coli protein
Occurring in:
  1. Adenomatous polyposis coli protein
IPR026818
Domain description: Adenomatous polyposis coli (APC) family
Occurring in:
  1. Adenomatous polyposis coli protein

Structure domain

CATH CATH domain
1.10.287.450
Class: Mainly Alpha
Architecture: Orthogonal Bundle
Topology: Helix Hairpins
Homology: Helix hairpin bin
Occurring in:
  1. Adenomatous polyposis coli protein
The deposited structure of PDB entry 1m5i contains 1 copy of CATH domain 1.10.287.450 (Helix Hairpins) in Adenomatous polyposis coli protein. Showing 1 copy in chain A.
SCOP SCOP annotation
82932
Class: Coiled coil proteins
Fold: Antiparallel coiled-coil
Superfamily: Tumor suppressor gene product Apc
Occurring in:
  1. Adenomatous polyposis coli protein
The deposited structure of PDB entry 1m5i contains 1 copy of SCOP domain 82932 (Tumor suppressor gene product Apc) in Adenomatous polyposis coli protein. Showing 1 copy in chain A.

Quick links