› 1mqm

X-ray diffraction
2.6Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:

Structure analysis Details

Assemblies composition:
hetero hexamer (preferred)
hetero dodecamer
Assembly name:
PDBe Complex ID:
PDB-CPX-137034 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (6 distinct):
Hemagglutinin HA1 chain Chains: A, D, G
Molecule details ›
Chains: A, D, G
Length: 329 amino acids
Theoretical weight: 36.29 KDa
Source organism: Influenza A virus
UniProt:
  • Canonical: P03442 (Residues: 17-345; Coverage: 60%)
Gene name: HA
Sequence domains: Haemagglutinin
Structure domains: Hemagglutinin (Ha1 Chain); Chain: A; domain 1
Hemagglutinin HA2 chain Chains: B, E, H
Molecule details ›
Chains: B, E, H
Length: 221 amino acids
Theoretical weight: 25.57 KDa
Source organism: Influenza A virus
UniProt:
  • Canonical: P03442 (Residues: 346-566; Coverage: 40%)
Gene name: HA
Sequence domains: Haemagglutinin
Structure domains: Hemagglutinin Ectodomain; Chain B

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer
Carbohydrate polymer : NEW Components: NAG, GAL, SIA
Carbohydrate polymer
Carbohydrate polymer : NEW Components: GAL, SIA
Carbohydrate polymer
1 bound ligand:
Ligand NAG 9 x NAG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 14-BM-C
Spacegroup: C2221
Unit cell:
a: 146.923Å b: 147.285Å c: 250.628Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.265 0.265 0.29

Quick links

Citations

21 review citations

Cross-species virus transmission and the emergence of new epidemic diseases.
Parrish et al. (2008)
20 more

17 mentions without citation

Sialic Acid Receptors of Viruses.
Matrosovich et al. (2015)
16 more