Function and Biology

Amylosucrase soaked with 1M sucrose

Source organism: Neisseria polysaccharea
Biochemical function: amylosucrase activity
Biological process: carbohydrate metabolic process
Cellular component: extracellular region

EC 2.4.1.4: Amylosucrase

Reaction catalysed:
Sucrose + ((1->4)-alpha-D-glucosyl)(n) = D-fructose + ((1->4)-alpha-D-glucosyl)(n+1)
Systematic name:
Sucrose:(1->4)-alpha-D-glucan 4-alpha-D-glucosyltransferase
Alternative Name(s):
  • Sucrose--glucan glucosyltransferase
  • Sucrose-1,4-sucrose:1,4-alpha-D-glucan 4-alpha-D-glucosyltransferase-glucan glucosyltransferase
  • Sucrose:1,4-alpha-D-glucan 4-alpha-D-glucosyltransferase

GO terms

Biochemical function:
Biological process:
Cellular component:

Sequence families

Pfam Protein families (Pfam)
PF22582
Domain description: Amylosucrase, C-terminal domain
Occurring in:
  1. Amylosucrase

PF00128
Domain description: Alpha amylase, catalytic domain
Occurring in:
  1. Amylosucrase
The deposited structure of PDB entry 1mw3 contains 1 copy of Pfam domain PF00128 (Alpha amylase, catalytic domain) in Amylosucrase. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR006047
Domain description: Glycosyl hydrolase, family 13, catalytic domain
Occurring in:
  1. Amylosucrase
IPR013780
Domain description: Glycosyl hydrolase, all-beta
Occurring in:
  1. Amylosucrase
IPR045857
Domain description: Oligo-1,6-glucosidase, domain 2
Occurring in:
  1. Amylosucrase
IPR044077
Domain description: Amylosucrase, catalytic domain
Occurring in:
  1. Amylosucrase
IPR017853
Domain description: Glycoside hydrolase superfamily
Occurring in:
  1. Amylosucrase

Structure domains

CATH CATH domains
3.20.20.80
Class: Alpha Beta
Architecture: Alpha-Beta Barrel
Topology: TIM Barrel
Homology: Glycosidases
Occurring in:
  1. Amylosucrase
The deposited structure of PDB entry 1mw3 contains 1 copy of CATH domain 3.20.20.80 (TIM Barrel) in Amylosucrase. Showing 1 copy in chain A.
2.60.40.1180
Class: Mainly Beta
Architecture: Sandwich
Topology: Immunoglobulin-like
Homology: Golgi alpha-mannosidase II
Occurring in:
  1. Amylosucrase
The deposited structure of PDB entry 1mw3 contains 1 copy of CATH domain 2.60.40.1180 (Immunoglobulin-like) in Amylosucrase. Showing 1 copy in chain A.
3.90.400.10
Class: Alpha Beta
Architecture: Alpha-Beta Complex
Topology: Oligo-1,6-glucosidase; domain 2
Homology: Oligo-1,6-glucosidase; Domain 2
Occurring in:
  1. Amylosucrase
The deposited structure of PDB entry 1mw3 contains 1 copy of CATH domain 3.90.400.10 (Oligo-1,6-glucosidase; domain 2) in Amylosucrase. Showing 1 copy in chain A.
1.10.1740.10
Class: Mainly Alpha
Architecture: Orthogonal Bundle
Topology: Rna Polymerase Sigma Factor; Chain: A
Homology: Rna Polymerase Sigma Factor; Chain: A
Occurring in:
  1. Amylosucrase
The deposited structure of PDB entry 1mw3 contains 1 copy of CATH domain 1.10.1740.10 (Rna Polymerase Sigma Factor; Chain: A) in Amylosucrase. Showing 1 copy in chain A.
SCOP SCOP annotations
51012
Class: All beta proteins
Fold: Glycosyl hydrolase domain
Superfamily: Glycosyl hydrolase domain
Occurring in:
  1. Amylosucrase
The deposited structure of PDB entry 1mw3 contains 1 copy of SCOP domain 51012 (alpha-Amylases, C-terminal beta-sheet domain) in Amylosucrase. Showing 1 copy in chain A.
51446
Class: Alpha and beta proteins (a/b)
Fold: TIM beta/alpha-barrel
Superfamily: (Trans)glycosidases
Occurring in:
  1. Amylosucrase
The deposited structure of PDB entry 1mw3 contains 1 copy of SCOP domain 51446 (Amylase, catalytic domain) in Amylosucrase. Showing 1 copy in chain A.