Function and Biology

tricorn protease in complex with Z-Phe-diketo-Arg-Glu-Phe

Source organism: Thermoplasma acidophilum
Biochemical function: serine-type peptidase activity
Biological process: proteolysis
Cellular component: cytoplasm

GO terms

Biochemical function:
Biological process:
Cellular component:

Sequence families

Pfam Protein families (Pfam)
PF03572
Domain description: Peptidase family S41
Occurring in:
  1. Tricorn protease
The deposited structure of PDB entry 1n6f contains 6 copies of Pfam domain PF03572 (Peptidase family S41) in Tricorn protease. Showing 1 copy in chain A.

PF14685
Domain description: Tricorn protease PDZ domain
Occurring in:
  1. Tricorn protease
The deposited structure of PDB entry 1n6f contains 6 copies of Pfam domain PF14685 (Tricorn protease PDZ domain) in Tricorn protease. Showing 1 copy in chain A.

PF14684
Domain description: Tricorn protease C1 domain
Occurring in:
  1. Tricorn protease
The deposited structure of PDB entry 1n6f contains 6 copies of Pfam domain PF14684 (Tricorn protease C1 domain) in Tricorn protease. Showing 1 copy in chain A.

PF07676
Domain description: WD40-like Beta Propeller Repeat
Occurring in:
  1. Tricorn protease
The deposited structure of PDB entry 1n6f contains 6 copies of Pfam domain PF07676 (WD40-like Beta Propeller Repeat) in Tricorn protease. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR005151
Domain description: Tail specific protease
Occurring in:
  1. Tricorn protease
IPR036034
Domain description: PDZ superfamily
Occurring in:
  1. Tricorn protease
IPR012393
Domain description: Tricorn protease
Occurring in:
  1. Tricorn protease
IPR029414
Domain description: Tricorn protease, PDZ domain
Occurring in:
  1. Tricorn protease
IPR028204
Domain description: Tricorn protease C1 domain
Occurring in:
  1. Tricorn protease
IPR029045
Domain description: ClpP/crotonase-like domain superfamily
Occurring in:
  1. Tricorn protease
IPR011659
Domain description: WD40-like beta propeller
Occurring in:
  1. Tricorn protease
IPR015943
Domain description: WD40/YVTN repeat-like-containing domain superfamily
Occurring in:
  1. Tricorn protease

Structure domains

CATH CATH domains
3.90.226.10
Class: Alpha Beta
Architecture: Alpha-Beta Complex
Topology: 2-enoyl-CoA Hydratase; Chain A, domain 1
Homology: 2-enoyl-CoA Hydratase; Chain A, domain 1
Occurring in:
  1. Tricorn protease
The deposited structure of PDB entry 1n6f contains 6 copies of CATH domain 3.90.226.10 (2-enoyl-CoA Hydratase; Chain A, domain 1) in Tricorn protease. Showing 1 copy in chain A.
2.30.42.10
Class: Mainly Beta
Architecture: Roll
Topology: Pdz3 Domain
Homology: Pdz3 Domain
Occurring in:
  1. Tricorn protease
The deposited structure of PDB entry 1n6f contains 6 copies of CATH domain 2.30.42.10 (Pdz3 Domain) in Tricorn protease. Showing 1 copy in chain A.
3.30.750.44
Class: Alpha Beta
Architecture: 2-Layer Sandwich
Topology: Transcription Regulator spoIIAA
Homology: Transcription Regulator spoIIAA
Occurring in:
  1. Tricorn protease
The deposited structure of PDB entry 1n6f contains 6 copies of CATH domain 3.30.750.44 (Transcription Regulator spoIIAA) in Tricorn protease. Showing 1 copy in chain A.
2.130.10.10
Class: Mainly Beta
Architecture: 7 Propeller
Topology: Methylamine Dehydrogenase; Chain H
Homology: YVTN repeat-like/Quinoprotein amine dehydrogenase
Occurring in:
  1. Tricorn protease
The deposited structure of PDB entry 1n6f contains 6 copies of CATH domain 2.130.10.10 (Methylamine Dehydrogenase; Chain H) in Tricorn protease. Showing 1 copy in chain A.
2.120.10.60
Class: Mainly Beta
Architecture: 6 Propeller
Topology: Neuraminidase
Homology: Tricorn protease N-terminal domain
Occurring in:
  1. Tricorn protease
The deposited structure of PDB entry 1n6f contains 6 copies of CATH domain 2.120.10.60 (Neuraminidase) in Tricorn protease. Showing 1 copy in chain A.
SCOP SCOP annotations
52100
Class: Alpha and beta proteins (a/b)
Fold: ClpP/crotonase
Superfamily: ClpP/crotonase
Occurring in:
  1. Tricorn protease
The deposited structure of PDB entry 1n6f contains 6 copies of SCOP domain 52100 (Tail specific protease, catalytic domain) in Tricorn protease. Showing 1 copy in chain A.
68933
Class: All beta proteins
Fold: PDZ domain-like
Superfamily: PDZ domain-like
Occurring in:
  1. Tricorn protease
The deposited structure of PDB entry 1n6f contains 6 copies of SCOP domain 68933 (Tail specific protease PDZ domain) in Tricorn protease. Showing 1 copy in chain A.
69323
Class: All beta proteins
Fold: 7-bladed beta-propeller
Superfamily: Tricorn protease domain 2
Occurring in:
  1. Tricorn protease
The deposited structure of PDB entry 1n6f contains 6 copies of SCOP domain 69323 (Tricorn protease domain 2) in Tricorn protease. Showing 1 copy in chain A.
69305
Class: All beta proteins
Fold: 6-bladed beta-propeller
Superfamily: Tricorn protease N-terminal domain
Occurring in:
  1. Tricorn protease
The deposited structure of PDB entry 1n6f contains 6 copies of SCOP domain 69305 (Tricorn protease N-terminal domain) in Tricorn protease. Showing 1 copy in chain A.