› 1ne5

Solution NMR

Solution Structure of HERG Specific Scorpion Toxin CnErg1

Released:
DOI: 10.2210/pdb1ne5/pdb
PDB entry 1ne5 coloured by chain, ensemble of 20 models, front view.
PDB entry 1ne5 coloured by chain, ensemble of 20 models, side view.
PDB entry 1ne5 coloured by chain, ensemble of 20 models, top view.
Source organism: Centruroides noxius
Primary publication:
Solution structure of CnErg1 (Ergtoxin), a HERG specific scorpion toxin.
Torres AM, Bansal P, Alewood PF, Bursill JA, Kuchel PW, Vandenberg JI
FEBS Lett 539 138-42 (2003)
PMID: 12650941

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-183141 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Potassium channel toxin gamma-KTx 1.1 Chain: A
Molecule details ›
Chain: A
Length: 42 amino acids
Theoretical weight: 4.75 KDa
Source organism: Centruroides noxius
Expression system: Not provided
UniProt:
  • Canonical: Q86QT3 (Residues: 21-62; Coverage: 100%)
Sequence domains: Ergtoxin family
Structure domains: Knottin, scorpion toxin-like

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing, molecular dynamics, distance geometry, torsion angle dynamics
Expression system: Not provided

Quick links

Citations

9 review citations

In silico pharmacology for drug discovery: applications to targets and beyond.
Ekins et al. (2007)
8 more

2 mentions without citation

RASMOT-3D PRO: a 3D motif search webserver.
Debret et al. (2009)
1 more