EC 6.3.2.6: Phosphoribosylaminoimidazolesuccinocarboxamide synthase
Reaction catalysed:
ATP + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + L-aspartate = ADP + phosphate + (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate
Systematic name:
5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate:L-aspartate ligase (ADP-forming)
Alternative Name(s):
- 4-((N-succinylamino)carbonyl)-5-aminoimidazole ribonucleotide synthetase
- 4-(N-succinocarboxamide)-5-aminoimidazole synthetase
- 5-aminoimidazole-4-N-succinocarboxamide ribonucleotide synthetase
- Phosphoribosylaminoimidazole-succinocarboxamide synthase
- Phosphoribosylaminoimidazole-succinocarboxamide synthetase
- Phosphoribosylaminoimidazolesuccinocarboxamide synthetase
- PurC
- SAICAR synthase
- SAICAR synthetase
- SAICARs
GO terms
Biochemical function:
Biological process:
Cellular component:
Sequence family
Protein family (Pfam)
InterPro annotations
Structure domains
CATH domains
3.30.470.20
Class:
Alpha Beta
Architecture:
2-Layer Sandwich
Topology:
D-amino Acid Aminotransferase; Chain A, domain 1
Homology:
ATP-grasp fold, B domain
Occurring in:
SCOP annotation