› 1oxv

X-ray diffraction
1.95Å resolution

Crystal structure of GlcV, the ABC-ATPase of the glucose ABC transporter from Sulfolobus solfataricus

Released:
DOI: 10.2210/pdb1oxv/pdb
PDB entry 1oxv coloured by chain, front view.
PDB entry 1oxv coloured by chain, side view.
PDB entry 1oxv coloured by chain, top view.
Source organism: Saccharolobus solfataricus
Primary publication:
Crystal structures of the ATPase subunit of the glucose ABC transporter from Sulfolobus solfataricus: nucleotide-free and nucleotide-bound conformations.
Verdon G, Albers SV, Dijkstra BW, Driessen AJ, Thunnissen AM
J Mol Biol 330 343-58 (2003)
PMID: 12823973

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-188982 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glucose import ATP-binding protein GlcV Chains: A, B, D
Molecule details ›
Chains: A, B, D
Length: 353 amino acids
Theoretical weight: 39.17 KDa
Source organism: Saccharolobus solfataricus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q97UY8 (Residues: 1-353; Coverage: 100%)
Gene names: SSO2850, glcV
Sequence domains:
Structure domains:

Ligands and Environments

3 bound ligands:
Ligand MG 3 x MG
Ligand IOD 38 x IOD
Ligand ANP 3 x ANP
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-2
Spacegroup: P212121
Unit cell:
a: 47.094Å b: 148.776Å c: 176.71Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.191 0.188 0.24
Expression system: Escherichia coli

Quick links

Citations

33 review citations

Structure, function, and evolution of bacterial ATP-binding cassette systems.
Davidson et al. (2008)
32 more

2 mentions without citation

In vivo phosphorylation of CFTR promotes formation of a nucleotide-binding domain heterodimer.
Mense et al. (2006)
1 more