EC 2.3.1.6: Choline O-acetyltransferase
Reaction catalysed:
Acetyl-CoA + choline = CoA + O-acetylcholine
Systematic name:
Acetyl-CoA:choline O-acetyltransferase
Alternative Name(s):
- CHOACTase
- Choline acetylase
- Choline acetyltransferase
GO terms
Biochemical function:
Biological process:
- response to ethanol
- rhythmic excitation
- neuron differentiation
- dendrite development
- response to xenobiotic stimulus
- acetylcholine biosynthetic process
- adult walking behavior
- rhythmic behavior
- memory
- response to nutrient
- establishment of synaptic specificity at neuromuscular junction
- muscle organ development
- neuromuscular synaptic transmission
- chemical synaptic transmission
- response to hypoxia
- antral ovarian follicle growth
Cellular component:
Sequence family
Protein family (Pfam)
InterPro annotations
Structure domains
CATH domains
3.30.559.10
Class:
Alpha Beta
Architecture:
2-Layer Sandwich
Topology:
Chloramphenicol Acetyltransferase
Homology:
Chloramphenicol acetyltransferase-like domain
Occurring in:
![The deposited structure of PDB entry <span class='highlight'>1q6x</span> contains 2 copies of CATH domain <span class='highlight'>3.30.559.10 (Chloramphenicol Acetyltransferase)</span> in <span class='highlight'>Choline O-acetyltransferase</span>. Showing 1 copy in chain <span class='highlight'>A</span>. The deposited structure of PDB entry 1q6x contains 2 copies of CATH domain 3.30.559.10 (Chloramphenicol Acetyltransferase) in Choline O-acetyltransferase. Showing 1 copy in chain A.](https://www.ebi.ac.uk/pdbe/static/entry/1q6x_1_A_CATH_3.30.559.10_image-200x200.png)