› 1q8s

X-ray diffraction
2.05Å resolution

Pterocarpus angolensis lectin (PAL) in complex with the dimannoside Man(alpha1-6)Man

Released:
DOI: 10.2210/pdb1q8s/pdb
PDB entry 1q8s coloured by chain, front view.
PDB entry 1q8s coloured by chain, side view.
PDB entry 1q8s coloured by chain, top view.
Source organism: Pterocarpus angolensis
Primary publication:
Structural basis of oligomannose recognition by the Pterocarpus angolensis seed lectin.
Loris R, Van Walle I, De Greve H, Beeckmans S, Deboeck F, Wyns L, Bouckaert J
J Mol Biol 335 1227-40 (2004)
PMID: 14729339

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-184567 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Legume lectin domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 252 amino acids
Theoretical weight: 27.56 KDa
Source organism: Pterocarpus angolensis
UniProt:
  • Canonical: Q8GSD2 (Residues: 9-260; Coverage: 97%)
Sequence domains: Legume lectin domain
Structure domains: Jelly Rolls

Ligands and Environments

Carbohydrate polymer : NEW Components: MMA, MAN
Carbohydrate polymer
2 bound ligands:
Ligand MN 2 x MN
Ligand CA 2 x CA
1 modified residue:
Ligand PCA 2 x PCA

Experiments and Validation Details

Entry percentile scores
X-ray source: EMBL/DESY, HAMBURG BEAMLINE X11
Spacegroup: P212121
Unit cell:
a: 56.88Å b: 83.38Å c: 122.57Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.185 0.182 0.216

Quick links

Citations

24 citation in other articles

Phytohemagglutinin from Phaseolus vulgaris (PHA-E) displays a novel glycan recognition mode using a common legume lectin fold.
Nagae et al. (2014)
23 more

1 mention without citation

Overview of the Structure⁻Function Relationships of Mannose-Specific Lectins from Plants, Algae and Fungi.
Barre et al. (2019)