› 1qor

X-ray diffraction
2.2Å resolution

CRYSTAL STRUCTURE OF ESCHERICHIA COLI QUINONE OXIDOREDUCTASE COMPLEXED WITH NADPH

Released:
DOI: 10.2210/pdb1qor/pdb
PDB entry 1qor coloured by chain, front view.
PDB entry 1qor coloured by chain, side view.
PDB entry 1qor coloured by chain, top view.
Source organism: Escherichia coli
Primary publication:
Crystal structure of Escherichia coli QOR quinone oxidoreductase complexed with NADPH.
Thorn JM, Barton JD, Dixon NE, Ollis DL, Edwards KJ
J Mol Biol 249 785-99 (1995)
PMID: 7602590

Function and Biology Details

Reaction catalysed: 
NADPH + 2 quinone = NADP(+) + 2 semiquinone
Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-151192 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Quinone oxidoreductase 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 327 amino acids
Theoretical weight: 35.21 KDa
Source organism: Escherichia coli
Expression system: Not provided
UniProt:
  • Canonical: P28304 (Residues: 1-327; Coverage: 100%)
Gene names: JW4011, b4051, hcz, qor, qor1, qorA
Sequence domains:
Structure domains:

Ligands and Environments


Cofactor: Ligand NDP 2 x NDP
1 bound ligand:
Ligand SO4 2 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P212121
Unit cell:
a: 107.44Å b: 104.06Å c: 77.45Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.14 0.14 not available
Expression system: Not provided

Quick links

Citations

6 review citations

The structures of type I polyketide synthases.
Keatinge-Clay AT. (2012)
5 more

15 mentions without citation

Polyketide stereocontrol: a study in chemical biology.
Weissman KJ. (2017)
14 more