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CRYSTAL STRUCTURE OF VIP2 WITH NAD

Source organism: Bacillus cereus
Biochemical function: not assigned
Biological process: not assigned
Cellular component: extracellular region

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EC 2.4.2.30: NAD(+) ADP-ribosyltransferase

Reaction catalysed:
NAD(+) + (ADP-D-ribosyl)(n)-acceptor = nicotinamide + (ADP-D-ribosyl)(n+1)-acceptor
Systematic name:
NAD(+):poly(ADP-D-ribosyl)-acceptor ADP-D-ribosyl-transferase
Alternative Name(s):
  • ADP-ribosyltransferase (polymerizing)
  • NAD(+):poly(adenine-diphosphate-D-ribosyl)-acceptor ADP-D-ribosyl-transferase
  • NAD(+):poly(adenosine-diphosphate-D-ribosyl)-acceptor ADP-D-ribosyl-transferase
  • Poly(ADP-ribose) synthase
  • Poly(ADP-ribose) synthetase
  • Poly(ADP-ribose)polymerase
  • Poly(adenosine diphosphate ribose) polymerase

GO terms

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:

Sequence family

Pfam Protein family (Pfam)
PF03496
Domain description: ADP-ribosyltransferase exoenzyme
Occurring in:
  1. ADP ribosyltransferase domain-containing protein
The deposited structure of PDB entry 1qs2 contains 2 copies of Pfam domain PF03496 (ADP-ribosyltransferase exoenzyme) in ADP ribosyltransferase domain-containing protein. Showing 2 copies in chain A.

InterPro InterPro annotations
IPR016013
Domain description: Binary exotoxin A, clostridial type
Occurring in:
  1. ADP ribosyltransferase domain-containing protein
IPR003540
Domain description: ADP ribosyltransferase
Occurring in:
  1. ADP ribosyltransferase domain-containing protein

Structure domain

CATH CATH domain
3.90.176.10
Class: Alpha Beta
Architecture: Alpha-Beta Complex
Topology: Toxin ADP-ribosyltransferase; Chain A, domain 1
Homology: Toxin ADP-ribosyltransferase; Chain A, domain 1
Occurring in:
  1. ADP ribosyltransferase domain-containing protein
The deposited structure of PDB entry 1qs2 contains 2 copies of CATH domain 3.90.176.10 (Toxin ADP-ribosyltransferase; Chain A, domain 1) in ADP ribosyltransferase domain-containing protein. Showing 2 copies in chain A.
SCOP SCOP annotation
56400
Class: Alpha and beta proteins (a+b)
Fold: ADP-ribosylation
Superfamily: ADP-ribosylation
Occurring in:
  1. ADP ribosyltransferase domain-containing protein
The deposited structure of PDB entry 1qs2 contains 2 copies of SCOP domain 56400 (ADP-ribosylating toxins) in ADP ribosyltransferase domain-containing protein. Showing 2 copies in chain A.

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