› 1r2l

Solution NMR

A parallel stranded DNA duplex with an A-G mismatch base-pair

Released:
DOI: 10.2210/pdb1r2l/pdb
PDB entry 1r2l coloured by chain, front view.
PDB entry 1r2l coloured by chain, side view.
PDB entry 1r2l coloured by chain, top view.
Source organism: Synthetic construct
Primary publication:
A parallel stranded DNA duplex with an A-G mismatch base-pair: (CCATAATTTACC:CCTATGAAATCC)
Venkitakrishnan RP, Bhaumik SR, Chary KVR, govil G, Liu K, Howard FB, Miles TH
RECENT TRENDS IN BIOPHYS.RES. 1-9 (2004)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-114486 (preferred)
Entry contents:
2 distinct DNA molecules
Macromolecules (2 distinct):
DNA (5'-D(P*(DNR)P*(DNR)P*DAP*DTP*DAP*DAP*DTP*DTP*DTP*DAP*(DNR)P*(DNR))-3') Chain: A
Molecule details ›
Chain: A
Length: 12 nucleotides
Theoretical weight: 3.59 KDa
Source organism: Synthetic construct
Expression system: Not provided
5'-D(P*CP*CP*TP*AP*TP*GP*AP*AP*AP*TP*CP*C)-3' Chain: B
Molecule details ›
Chain: B
Length: 12 nucleotides
Theoretical weight: 3.61 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
1 modified residue:
Ligand DNR 4 x DNR

Experiments and Validation Details

Entry percentile scores
Refinement method: From the structure 1JUU, the required T base was replaced by G using insightII.
Expression system: Not provided

Quick links

Citations

1 mention without citation

Electrochemical, spectroscopic and theoretical monitoring of anthracyclines' interactions with DNA and ascorbic acid by adopting two routes: Cancer cell line studies.
Perveen et al. (2018)