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N-Truncated Human Cystatin C; Dimeric Form With 3D Domain Swapping

Source organism: Homo sapiens
Biochemical function: identical protein binding
Biological process: supramolecular fiber organization
Cellular component: ficolin-1-rich granule lumen

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GO terms

Biochemical function:
Biological process:
Cellular component:

Sequence family

Pfam Protein family (Pfam)
PF00031
Domain description: Cystatin domain
Occurring in:
  1. Cystatin-C
The deposited structure of PDB entry 1r4c contains 8 copies of Pfam domain PF00031 (Cystatin domain) in Cystatin-C. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR000010
Domain description: Cystatin domain
Occurring in:
  1. Cystatin-C
IPR018073
Domain description: Proteinase inhibitor I25, cystatin, conserved site
Occurring in:
  1. Cystatin-C
IPR046350
Domain description: Cystatin superfamily
Occurring in:
  1. Cystatin-C

Structure domain

CATH CATH domain
3.10.450.10
Class: Alpha Beta
Architecture: Roll
Topology: Nuclear Transport Factor 2; Chain: A,
Homology: Nuclear Transport Factor 2; Chain: A,
Occurring in:
  1. Cystatin-C
The deposited structure of PDB entry 1r4c contains 8 copies of CATH domain 3.10.450.10 (Nuclear Transport Factor 2; Chain: A,) in Cystatin-C. Showing 1 copy in chain A.
SCOP SCOP annotation
54407
Class: Alpha and beta proteins (a+b)
Fold: Cystatin-like
Superfamily: Cystatin/monellin
Occurring in:
  1. Cystatin-C
The deposited structure of PDB entry 1r4c contains 8 copies of SCOP domain 54407 (Cystatins) in Cystatin-C. Showing 1 copy in chain A.

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