EC 3.1.3.48: Protein-tyrosine-phosphatase
Reaction catalysed:
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate
Systematic name:
Protein-tyrosine-phosphate phosphohydrolase
Alternative Name(s):
- (Phosphotyrosine)protein phosphatase
- PPT-phosphatase
- PTP-phosphatase
- PTPase
- Phosphoprotein phosphatase (phosphotyrosine)
- Phosphotyrosine histone phosphatase
- Phosphotyrosine phosphatase
- Phosphotyrosine protein phosphatase
- Phosphotyrosylprotein phosphatase
- Protein phosphotyrosine phosphatase
- Tyrosine O-phosphate phosphatase
- Tyrosylprotein phosphatase
GO terms
Biochemical function:
Biological process:
- cellular response to leukemia inhibitory factor
- positive regulation of establishment of protein localization
- positive regulation of non-canonical NF-kappaB signal transduction
- regulation of vascular endothelial growth factor signaling pathway
- endothelial cell migration
- positive regulation of vascular permeability
- dephosphorylation
- Notch signaling pathway
- protein dephosphorylation
- regulation of DNA-templated transcription
Protein family (Pfam)
InterPro annotations
CATH domain
SCOP annotation