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Solution structure of the C-terminal domain of p63

Source organism: Homo sapiens
Biochemical function: DNA-binding transcription factor activity
Biological process: apoptotic process
Cellular component: nucleus

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GO terms

Sequence family

Pfam Protein family (Pfam)
PF07647
Domain description: SAM domain (Sterile alpha motif)
Occurring in:
  1. Tumor protein 63
The deposited structure of PDB entry 1rg6 contains 1 copy of Pfam domain PF07647 (SAM domain (Sterile alpha motif)) in Tumor protein 63. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR001660
Domain description: Sterile alpha motif domain
Occurring in:
  1. Tumor protein 63
IPR013761
Domain description: Sterile alpha motif/pointed domain superfamily
Occurring in:
  1. Tumor protein 63
IPR002117
Domain description: p53 tumour suppressor family
Occurring in:
  1. Tumor protein 63
IPR037611
Domain description: Tumour protein p63, SAM domain
Occurring in:
  1. Tumor protein 63

Structure domain

CATH CATH domain
1.10.150.50
Class: Mainly Alpha
Architecture: Orthogonal Bundle
Topology: DNA polymerase; domain 1
Homology: Transcription Factor, Ets-1
Occurring in:
  1. Tumor protein 63
The deposited structure of PDB entry 1rg6 contains 1 copy of CATH domain 1.10.150.50 (DNA polymerase; domain 1) in Tumor protein 63. Showing 1 copy in chain A.
SCOP SCOP annotation
47773
Class: All alpha proteins
Fold: SAM domain-like
Superfamily: SAM/Pointed domain
Occurring in:
  1. Tumor protein 63
The deposited structure of PDB entry 1rg6 contains 1 copy of SCOP domain 47773 (SAM (sterile alpha motif) domain) in Tumor protein 63. Showing 1 copy in chain A.

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