Function and Biology

THE STRUCTURE OF PENTAMERIC HUMAN SERUM AMYLOID P COMPONENT

Source organism: Homo sapiens
Biochemical function: unfolded protein binding
Biological process: negative regulation of glycoprotein metabolic process
Cellular component: blood microparticle

Sequence family

Pfam Protein family (Pfam)
PF00354
Domain description: Pentaxin family
Occurring in:
  1. Serum amyloid P-component
The deposited structure of PDB entry 1sac contains 5 copies of Pfam domain PF00354 (Pentaxin family) in Serum amyloid P-component. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR001759
Domain description: Pentraxin-related
Occurring in:
  1. Serum amyloid P-component
IPR030476
Domain description: Pentaxin, conserved site
Occurring in:
  1. Serum amyloid P-component
IPR013320
Domain description: Concanavalin A-like lectin/glucanase domain superfamily
Occurring in:
  1. Serum amyloid P-component

Structure domain

CATH CATH domain
2.60.120.200
Class: Mainly Beta
Architecture: Sandwich
Topology: Jelly Rolls
Homology: Jelly Rolls
Occurring in:
  1. Serum amyloid P-component
The deposited structure of PDB entry 1sac contains 5 copies of CATH domain 2.60.120.200 (Jelly Rolls) in Serum amyloid P-component. Showing 1 copy in chain A.
SCOP SCOP annotation
49951
Class: All beta proteins
Fold: Concanavalin A-like lectins/glucanases
Superfamily: Concanavalin A-like lectins/glucanases
Occurring in:
  1. Serum amyloid P-component
The deposited structure of PDB entry 1sac contains 5 copies of SCOP domain 49951 (Pentraxin (pentaxin)) in Serum amyloid P-component. Showing 1 copy in chain A.