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X-ray structure of [Lys(-2)-Arg(-1)-des(17-21)]-endothelin-1 peptide

Source organism: Homo sapiens
Biochemical function: not assigned
Biological process: regulation of vasoconstriction
Cellular component: extracellular region

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GO terms

Biochemical function:
  • not assigned
Biological process:
Cellular component:

Sequence family

Pfam Protein family (Pfam)
PF00322
Domain description: Endothelin family
Occurring in:
  1. Endothelin-1
The deposited structure of PDB entry 1t7h contains 2 copies of Pfam domain PF00322 (Endothelin family) in Endothelin-1. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR020475
Domain description: Endothelin
Occurring in:
  1. Endothelin-1
IPR001928
Domain description: Endothelin-like toxin
Occurring in:
  1. Endothelin-1
IPR019764
Domain description: Endothelin-like toxin, conserved site
Occurring in:
  1. Endothelin-1

Structure domain

SCOP SCOP annotation
58451
Class: Peptides
Fold: Endothelin-like
Superfamily: Endothelin-like
Occurring in:
  1. Endothelin-1
The deposited structure of PDB entry 1t7h contains 2 copies of SCOP domain 58451 (Endothelin-like) in Endothelin-1. Showing 1 copy in chain A.

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