Reviews - 1t8i mentioned but not cited (8)
- DNA topoisomerases and their poisoning by anticancer and antibacterial drugs. Pommier Y, Leo E, Zhang H, Marchand C. Chem Biol 17 421-433 (2010)
- Drugging topoisomerases: lessons and challenges. Pommier Y. ACS Chem Biol 8 82-95 (2013)
- Interfacial inhibitors: targeting macromolecular complexes. Pommier Y, Marchand C. Nat Rev Drug Discov 11 25-36 (2011)
- DNA topoisomerases: Advances in understanding of cellular roles and multi-protein complexes via structure-function analysis. McKie SJ, Neuman KC, Maxwell A. Bioessays 43 e2000286 (2021)
- Interfacial inhibitors. Pommier Y, Kiselev E, Marchand C. Bioorg Med Chem Lett 25 3961-3965 (2015)
- DNA folds threaten genetic stability and can be leveraged for chemotherapy. Zell J, Rota Sperti F, Britton S, Monchaud D. RSC Chem Biol 2 47-76 (2021)
- Indole-Based Tubulin Inhibitors: Binding Modes and SARs Investigations. Tang S, Zhou Z, Jiang Z, Zhu W, Qiao D. Molecules 27 1587 (2022)
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Articles - 1t8i mentioned but not cited (61)
- Ligand-based Pharmacophore Modeling, Virtual Screening and Molecular Docking Studies for Discovery of Potential Topoisomerase I Inhibitors. Pal S, Kumar V, Kundu B, Bhattacharya D, Preethy N, Reddy MP, Talukdar A. Comput Struct Biotechnol J 17 291-310 (2019)
- Design, synthesis, and biological evaluation of 14-substituted aromathecins as topoisomerase I inhibitors. Cinelli MA, Morrell A, Dexheimer TS, Scher ES, Pommier Y, Cushman M. J Med Chem 51 4609-4619 (2008)
- Antiproliferative activities of Amaryllidaceae alkaloids from Lycoris radiata targeting DNA topoisomerase I. Chen GL, Tian YQ, Wu JL, Li N, Guo MQ. Sci Rep 6 38284 (2016)
- Exploring DNA topoisomerase I ligand space in search of novel anticancer agents. Drwal MN, Agama K, Wakelin LP, Pommier Y, Griffith R. PLoS One 6 e25150 (2011)
- Alcohol-, diol-, and carbohydrate-substituted indenoisoquinolines as topoisomerase I inhibitors: investigating the relationships involving stereochemistry, hydrogen bonding, and biological activity. Peterson KE, Cinelli MA, Morrell AE, Mehta A, Dexheimer TS, Agama K, Antony S, Pommier Y, Cushman M. J Med Chem 54 4937-4953 (2011)
- New Discorhabdin Alkaloids from the Antarctic Deep-Sea Sponge Latrunculia biformis. Li F, Peifer C, Janussen D, Tasdemir D. Mar Drugs 17 E439 (2019)
- Targeted Isolation of Tsitsikammamines from the Antarctic Deep-Sea Sponge Latrunculia biformis by Molecular Networking and Anticancer Activity. Li F, Janussen D, Peifer C, Pérez-Victoria I, Tasdemir D. Mar Drugs 16 (2018)
- Effect of Pterostilbene, a Natural Derivative of Resveratrol, in the Treatment of Colorectal Cancer through Top1/Tdp1-Mediated DNA Repair Pathway. Zhang Y, Li Y, Sun C, Chen X, Han L, Wang T, Liu J, Chen X, Zhao D. Cancers (Basel) 13 4002 (2021)
- Identification of Leishmania donovani Topoisomerase 1 inhibitors via intuitive scaffold hopping and bioisosteric modification of known Top 1 inhibitors. Mamidala R, Majumdar P, Jha KK, Bathula C, Agarwal R, Chary MT, Majumder HK, Munshi P, Sen S. Sci Rep 6 26603 (2016)
- Molecular docking and dynamics simulation study of bioactive compounds from Ficus carica L. with important anticancer drug targets. Gurung AB, Ali MA, Lee J, Farah MA, Al-Anazi KM. PLoS One 16 e0254035 (2021)
- The structure-activity relationships of A-ring-substituted aromathecin topoisomerase I inhibitors strongly support a camptothecin-like binding mode. Cinelli MA, Morrell AE, Dexheimer TS, Agama K, Agrawal S, Pommier Y, Cushman M. Bioorg Med Chem 18 5535-5552 (2010)
- Design, Synthesis, Antimicrobial, and Anticancer Activities of Acridine Thiosemicarbazides Derivatives. Chen R, Huo L, Jaiswal Y, Huang J, Zhong Z, Zhong J, Williams L, Xia X, Liang Y, Yan Z. Molecules 24 E2065 (2019)
- Design, synthesis, cytotoxic activity and molecular docking studies of new 20(S)-sulfonylamidine camptothecin derivatives. Song ZL, Wang MJ, Li L, Wu D, Wang YH, Yan LT, Morris-Natschke SL, Liu YQ, Zhao YL, Wang CY, Liu H, Goto M, Liu H, Zhu GX, Lee KH. Eur J Med Chem 115 109-120 (2016)
- Hybrid topoisomerase I and HDAC inhibitors as dual action anticancer agents. Cincinelli R, Musso L, Artali R, Guglielmi MB, La Porta I, Melito C, Colelli F, Cardile F, Signorino G, Fucci A, Frusciante M, Pisano C, Dallavalle S. PLoS One 13 e0205018 (2018)
- Inhibitory effect of DNA topoisomerase inhibitor isoliquiritigenin on the growth of glioma cells. Zhao S, Chang H, Ma P, Gao G, Jin C, Zhao X, Zhou W, Jin B. Int J Clin Exp Pathol 8 12577-12582 (2015)
- Antileishmanial activity of terpenylquinones on Leishmania infantum and their effects on Leishmania topoisomerase IB. Pérez-Pertejo Y, Escudero-Martínez JM, Reguera RM, Balaña-Fouce R, García PA, Jambrina PG, San Feliciano A, Castro MÁ. Int J Parasitol Drugs Drug Resist 11 70-79 (2019)
- Artemisinin Derivatives with Antimelanoma Activity Show Inhibitory Effect against Human DNA Topoisomerase 1. Botta L, Filippi S, Zippilli C, Cesarini S, Bizzarri BM, Cirigliano A, Rinaldi T, Paiardini A, Fiorucci D, Saladino R, Negri R, Benedetti P. ACS Med Chem Lett 11 1035-1040 (2020)
- Mutational study of the "catalytic tetrad" of DNA topoisomerase IB from the hemoflagellate Leishmania donovani: Role of Asp-353 and Asn-221 in camptothecin resistance. Diaz-González R, Pérez-Pertejo Y, Pommier Y, Balaña-Fouce R, Reguera RM. Biochem Pharmacol 76 608-619 (2008)
- New 1,2,3-triazole linked ciprofloxacin-chalcones induce DNA damage by inhibiting human topoisomerase I& II and tubulin polymerization. Mohammed HHH, Abd El-Hafeez AA, Ebeid K, Mekkawy AI, Abourehab MAS, Wafa EI, Alhaj-Suliman SO, Salem AK, Ghosh P, Abuo-Rahma GEA, Hayallah AM, Abbas SH. J Enzyme Inhib Med Chem 37 1346-1363 (2022)
- Chromenopyrimidinone Controls Stemness and Malignancy by suppressing CD133 Expression in Hepatocellular Carcinoma. Song Y, Kim S, Lee H, No JH, Ryu HC, Kim J, Lim JW, Kim M, Choi I, Seo HR. Cancers (Basel) 12 E1193 (2020)
- Phenolic metabolites, biological activities, and isolated compounds of Terminalia muelleri extract. El-Kashak WA, Osman SM, Gaara AH, El-Toumy SA, Mohamed TK, Brouard I. Pharm Biol 55 2277-2284 (2017)
- Adaptive laboratory evolution in S. cerevisiae highlights role of transcription factors in fungal xenobiotic resistance. Ottilie S, Luth MR, Hellemann E, Goldgof GM, Vigil E, Kumar P, Cheung AL, Song M, Godinez-Macias KP, Carolino K, Yang J, Lopez G, Abraham M, Tarsio M, LeBlanc E, Whitesell L, Schenken J, Gunawan F, Patel R, Smith J, Love MS, Williams RM, McNamara CW, Gerwick WH, Ideker T, Suzuki Y, Wirth DF, Lukens AK, Kane PM, Cowen LE, Durrant JD, Winzeler EA. Commun Biol 5 128 (2022)
- Antitumor Activity and Mechanism of Robustic Acid from Dalbergia benthami Prain via Computational Target Fishing. Huang J, Liang Y, Tian W, Ma J, Huang L, Li B, Chen R, Li D. Molecules 25 E3919 (2020)
- Development of purely structure-based pharmacophores for the topoisomerase I-DNA-ligand binding pocket. Drwal MN, Agama K, Pommier Y, Griffith R. J Comput Aided Mol Des 27 1037-1049 (2013)
- Lignin Nanoparticles Deliver Novel Thymine Biomimetic Photo-Adducts with Antimelanoma Activity. Gabellone S, Piccinino D, Filippi S, Castrignanò T, Zippilli C, Del Buono D, Saladino R. Int J Mol Sci 23 915 (2022)
- Machine Learning Models Combined with Virtual Screening and Molecular Docking to Predict Human Topoisomerase I Inhibitors. Li B, Kang X, Zhao D, Zou Y, Huang X, Wang J, Zhang C. Molecules 24 E2107 (2019)
- Natural Product Evodiamine with Borate Trigger Unit: Discovery of Potent Antitumor Agents against Colon Cancer. Li X, Wu S, Dong G, Chen S, Ma Z, Liu D, Sheng C. ACS Med Chem Lett 11 439-444 (2020)
- Newly Synthesized Imino-Derivatives Analogues of Resveratrol Exert Inhibitory Effects in Breast Tumor Cells. Iacopetta D, Lappano R, Mariconda A, Ceramella J, Sinicropi MS, Saturnino C, Talia M, Cirillo F, Martinelli F, Puoci F, Rosano C, Longo P, Maggiolini M. Int J Mol Sci 21 E7797 (2020)
- Structure-Based Drug Design and Identification of H2O-Soluble and Low Toxic Hexacyclic Camptothecin Derivatives with Improved Efficacy in Cancer and Lethal Inflammation Models in Vivo. Pan P, Chen J, Li X, Li M, Yu H, Zhao JJ, Ni J, Wang X, Sun H, Tian S, Zhu F, Liu F, Huang Y, Hou T. J Med Chem 61 8613-8624 (2018)
- TOP1-DNA Trapping by Exatecan and Combination Therapy with ATR Inhibitor. Jo U, Murai Y, Agama KK, Sun Y, Saha LK, Yang X, Arakawa Y, Gayle S, Jones K, Paralkar V, Sundaram RK, Van Doorn J, Vasquez JC, Bindra RS, Choi WS, Pommier Y. Mol Cancer Ther 21 1090-1102 (2022)
- In Vitro and In Silico Characterization of an Antimalarial Compound with Antitumor Activity Targeting Human DNA Topoisomerase IB. Soren BC, Babu Dasari J, Ottaviani A, Messina B, Andreotti G, Romeo A, Iacovelli F, Falconi M, Desideri A, Fiorani P. Int J Mol Sci 22 7455 (2021)
- topIb, a phylogenetic hallmark gene of Thaumarchaeota encodes a functional eukaryote-like topoisomerase IB. Dahmane N, Gadelle D, Delmas S, Criscuolo A, Eberhard S, Desnoues N, Collin S, Zhang H, Pommier Y, Forterre P, Sezonov G. Nucleic Acids Res 44 2795-2805 (2016)
- A Novel Benzocoumarin-Stilbene Hybrid as a DNA ligase I inhibitor with in vitro and in vivo anti-tumor activity in breast cancer models. Hussain MK, Singh DK, Singh A, Asad M, Ansari MI, Shameem M, Krishna S, Valicherla GR, Makadia V, Meena S, Deshmukh AL, Gayen JR, Imran Siddiqi M, Datta D, Hajela K, Banerjee D. Sci Rep 7 10715 (2017)
- Dual Topoisomerase I/II Inhibition-Induced Apoptosis and Necro-Apoptosis in Cancer Cells by a Novel Ciprofloxacin Derivative via RIPK1/RIPK3/MLKL Activation. Alaaeldin R, Abdel-Rahman IM, Ali FEM, Bekhit AA, Elhamadany EY, Zhao QL, Cui ZG, Fathy M. Molecules 27 7993 (2022)
- Exploring Multifunctional Bioactive Components from Podophyllum sinense Using Multi-Target Ultrafiltration. Feng H, Chen G, Zhang Y, Guo M. Front Pharmacol 12 749189 (2021)
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- Network pharmacology and RNA sequencing studies on triterpenoid saponins from Bupleurum chinense for the treatment of breast cancer. Li D, Liu D, Yue D, Gao P, Du C, Liu X, Zhang L. RSC Adv 9 41088-41098 (2019)
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- Molecular docking elucidates the plausible mechanisms underlying the anticancer properties of acetyldigitoxigenin from Adenium obesum. Gurung AB, Ali MA, Lee J, Al-Hemaid F, Farah MA, Al-Anazi KM. Saudi J Biol Sci 27 1907-1911 (2020)
- Novel Sophoridine Derivatives Bearing Phosphoramide Mustard Moiety Exhibit Potent Antitumor Activities In Vitro and In Vivo. Li D, Dai L, Zhao X, Zhi S, Shen H, Yang Z. Molecules 23 E1960 (2018)
- Novel α, β-Unsaturated Sophoridinic Derivatives: Design, Synthesis, Molecular Docking and Anti-Cancer Activities. Xu Y, Wu L, Dai H, Gao M, Ur Rashid H, Wang H, Xie P, Liu X, Jiang J, Wang L. Molecules 22 E1967 (2017)
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- Characterization of Promising Cytotoxic Metabolites from Tabebuia guayacan Hemsl.: Computational Prediction and In Vitro Testing. El-Hawary SS, Mohammed R, Taher MA, AbouZid SF, Mansour MA, Almahmoud SA, Huwaimel B, Amin E. Plants (Basel) 11 888 (2022)
- Design and Synthesis of Acridine-Triazole and Acridine-Thiadiazole Derivatives and Their Inhibitory Effect against Cancer Cells. Huo L, Liu X, Jaiswal Y, Xu H, Chen R, Lu R, Nong Y, Williams L, Liang Y, Jia Z. Int J Mol Sci 24 64 (2022)
- Evodiamine and Rutaecarpine as Potential Anticancer Compounds: A Combined Computational Study. Liu J, Guo H, Zhou J, Wang Y, Yan H, Jin R, Tang Y. Int J Mol Sci 23 11513 (2022)
- Insight on the Interaction between the Camptothecin Derivative and DNA Oligomer Mimicking the Target of Topo I Inhibitors. Bocian W, Naumczuk B, Urbanowicz M, Sitkowski J, Bednarek E, Wiktorska K, Pogorzelska A, Wielgus E, Kozerski L. Molecules 27 6946 (2022)
- Molecular Docking and Dynamics Simulation Revealed the Potential Inhibitory Activity of New Drugs against Human Topoisomerase I Receptor. Madeddu F, Di Martino J, Pieroni M, Del Buono D, Bottoni P, Botta L, Castrignanò T, Saladino R. Int J Mol Sci 23 14652 (2022)
- Novel bivalent securinine mimetics as topoisomerase I inhibitors. Hou W, Lin H, Wang ZY, Banwell MG, Zeng T, Sun PH, Lin J, Chen WM. Medchemcomm 8 320-328 (2017)
- Potential Multifunctional Bioactive Compounds from Dysosma versipellis Explored by Bioaffinity Ultrafiltration-HPLC/MS with Topo I, Topo II, COX-2 and ACE2. Feng H, Chen G, Zhang Y, Guo M. J Inflamm Res 15 4677-4692 (2022)
- Synthesis, anticancer evaluation and molecular docking studies of new benzimidazole- 1,3,4-oxadiazole derivatives as human topoisomerase types I poison. Acar Çevik U, Sağlık BN, Osmaniye D, Levent S, Kaya Çavuşoğlu B, Karaduman AB, Atlıd Ö, Atlı Eklioğlu Ö, Kaplancıklı ZA. J Enzyme Inhib Med Chem 35 1657-1673 (2020)
- Combination of bioaffinity ultrafiltration-UFLC-ESI-Q/TOF-MS/MS, in silico docking and multiple complex networks to explore antitumor mechanism of topoisomerase I inhibitors from Artemisiae Scopariae Herba. Chen T, Hu J, Wang H, Tan N, Qi J, Wang X, Wang L. BMC Complement Med Ther 23 317 (2023)
- Design and synthesis of new spirooxindole candidates and their selenium nanoparticles as potential dual Topo I/II inhibitors, DNA intercalators, and apoptotic inducers. El-Kalyoubi S, Khalifa MM, Abo-Elfadl MT, El-Sayed AA, Elkamhawy A, Lee K, Al-Karmalawy AA. J Enzyme Inhib Med Chem 38 2242714 (2023)
- Dimethylmyricacene: An In Vitro and In Silico Study of a Semisynthetic Non-Camptothecin Derivative Compound, Targeting Human DNA Topoisomerase 1B. Ottaviani A, Iacovelli F, Welsch J, Morozzo Della Rocca B, Desideri A, Falconi M, Calcul L, Baker BJ, Fiorani P. Cells 11 3486 (2022)
- MD-Ligand-Receptor: A High-Performance Computing Tool for Characterizing Ligand-Receptor Binding Interactions in Molecular Dynamics Trajectories. Pieroni M, Madeddu F, Di Martino J, Arcieri M, Parisi V, Bottoni P, Castrignanò T. Int J Mol Sci 24 11671 (2023)
- Molecular Dynamics Investigations of Human DNA-Topoisomerase I Interacting with Novel Dewar Valence Photo-Adducts: Insights into Inhibitory Activity. Di Martino J, Arcieri M, Madeddu F, Pieroni M, Carotenuto G, Bottoni P, Botta L, Castrignanò T, Gabellone S, Saladino R. Int J Mol Sci 25 234 (2023)
- New 5-Substituted SN38 Derivatives: A Stability Study and Interaction with Model Nicked DNA by NMR and Molecular Modeling Methods. Bednarek E, Bocian W, Sitkowski J, Urbanowicz M, Kozerski L. Int J Mol Sci 24 17445 (2023)
- Novel 3,9-Disubstituted Acridines with Strong Inhibition Activity against Topoisomerase I: Synthesis, Biological Evaluation and Molecular Docking Study. Krochtová K, Halečková A, Janovec L, Blizniaková M, Kušnírová K, Kožurková M. Molecules 28 1308 (2023)
- Synthesis of novel amidines via one-pot three component reactions: Selective topoisomerase I inhibitors with antiproliferative properties. El-Sheref EM, Tawfeek HN, Hassan AA, Bräse S, Elbastawesy MAI, Gomaa HAM, Mostafa YA, Youssif BGM. Front Chem 10 1039176 (2022)
- The binding proximity of methyl β-lilacinobioside isolated from Caralluma retrospiciens with topoisomerase II attributes apoptosis in breast cancer cell line. Alallah MI, Alhemaid F, Bai F, Mothana RA, Elshikh MS, Abul Farah M, Ali MA, Lee J, Al-Anazi KM. Saudi J Biol Sci 25 1826-1833 (2018)
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- A novel norindenoisoquinoline structure reveals a common interfacial inhibitor paradigm for ternary trapping of the topoisomerase I-DNA covalent complex. Marchand C, Antony S, Kohn KW, Cushman M, Ioanoviciu A, Staker BL, Burgin AB, Stewart L, Pommier Y. Mol Cancer Ther 5 287-295 (2006)
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