Function and Biology

Crystal structure of fructose-1,6-bisphosphatase

Source organism: Sulfurisphaera tokodaii str. 7
Biochemical function: metal ion binding
Biological process: dephosphorylation
Cellular component: not assigned

EC 4.1.2.13: Fructose-bisphosphate aldolase

Reaction catalysed:
D-fructose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde 3-phosphate
Systematic name:
D-fructose-1,6-bisphosphate D-glyceraldehyde-3-phosphate-lyase (glycerone-phosphate-forming)
Alternative Name(s):
  • 1,6-diphosphofructose aldolase
  • Aldolase
  • D-fructose-1,6-bisphosphate D-glyceraldehyde-3-phosphate-lyase
  • Diphosphofructose aldolase
  • Fructoaldolase
  • Fructose 1,6-diphosphate aldolase
  • Fructose 1-monophosphate aldolase
  • Fructose 1-phosphate aldolase
  • Fructose diphosphate aldolase
  • Fructose-1,6-bisphosphate triosephosphate-lyase
  • Ketose 1-phosphate aldolase
  • Phosphofructoaldolase
  • SMALDO
  • Zymohexase

EC 3.1.3.11: Fructose-bisphosphatase

Reaction catalysed:
D-fructose 1,6-bisphosphate + H(2)O = D-fructose 6-phosphate + phosphate
Systematic name:
D-fructose-1,6-bisphosphate 1-phosphohydrolase
Alternative Name(s):
  • D-fructose 1,6-diphosphatase
  • D-fructose-1,6-bisphosphate phosphatase
  • FBPase
  • Fructose 1,6-bisphosphatase
  • Fructose 1,6-bisphosphate 1-phosphatase
  • Fructose 1,6-bisphosphate phosphatase
  • Fructose 1,6-diphosphatase
  • Fructose 1,6-diphosphate phosphatase
  • Fructose bisphosphate phosphatase
  • Fructose diphosphatase
  • Fructose diphosphate phosphatase
  • Hexose bisphosphatase
  • Hexose diphosphatase

Sequence family

Pfam Protein family (Pfam)
PF01950
Domain description: Fructose-1,6-bisphosphatase
Occurring in:
  1. Fructose-1,6-bisphosphate aldolase/phosphatase
The deposited structure of PDB entry 1umg contains 1 copy of Pfam domain PF01950 (Fructose-1,6-bisphosphatase) in Fructose-1,6-bisphosphate aldolase/phosphatase. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR002803
Domain description: Fructose-1,6-bisphosphatase, class V
Occurring in:
  1. Fructose-1,6-bisphosphate aldolase/phosphatase
IPR036076
Domain description: Fructose-1,6-bisphosphatase, class V superfamily
Occurring in:
  1. Fructose-1,6-bisphosphate aldolase/phosphatase

Structure domain

SCOP SCOP annotation
111250
Class: Alpha and beta proteins (a+b)
Fold: Sulfolobus fructose-1,6-bisphosphatase-like
Superfamily: Sulfolobus fructose-1,6-bisphosphatase-like
Occurring in:
  1. Fructose-1,6-bisphosphate aldolase/phosphatase
The deposited structure of PDB entry 1umg contains 1 copy of SCOP domain 111250 (Sulfolobus fructose-1,6-bisphosphatase-like) in Fructose-1,6-bisphosphate aldolase/phosphatase. Showing 1 copy in chain A.