Function and Biology

Solution Structure of the PB1 domain of PKCiota

Source organism: Homo sapiens
Biochemical function: not assigned
Biological process: not assigned
Cellular component: not assigned

EC 2.7.11.13: Protein kinase C

Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein
Systematic name:
ATP:protein phosphotransferase (diacylglycerol-dependent)
Alternative Name(s):
  • CPKC
  • CPKC-alpha
  • CPKC-beta
  • CPKC-gamma
  • Calcium-dependent protein kinase C
  • Calcium-independent protein kinase C
  • Calcium/phospholipid dependent protein kinase
  • NPKC
  • NPKC-delta
  • NPKC-epsilon
  • NPKC-eta
  • NPKC-theta
  • PKC
  • PKC-alpha
  • PKC-beta
  • PKC-delta
  • PKC-epsilon
  • PKC-gamma
  • PKC-zeta
  • Pkc1p
  • Protein kinase C-epsilon
  • STK24

GO terms

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence family

Pfam Protein family (Pfam)
PF00564
Domain description: PB1 domain
Occurring in:
  1. Protein kinase C iota type
The deposited structure of PDB entry 1vd2 contains 1 copy of Pfam domain PF00564 (PB1 domain) in Protein kinase C iota type. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR000270
Domain description: PB1 domain
Occurring in:
  1. Protein kinase C iota type
IPR034877
Domain description: Protein kinase C, PB1 domain
Occurring in:
  1. Protein kinase C iota type

Structure domain

CATH CATH domain
3.10.20.90
Class: Alpha Beta
Architecture: Roll
Topology: Ubiquitin-like (UB roll)
Homology: Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1
Occurring in:
  1. Protein kinase C iota type
The deposited structure of PDB entry 1vd2 contains 1 copy of CATH domain 3.10.20.90 (Ubiquitin-like (UB roll)) in Protein kinase C iota type. Showing 1 copy in chain A.
SCOP SCOP annotation
64225
Class: Alpha and beta proteins (a+b)
Fold: beta-Grasp (ubiquitin-like)
Superfamily: CAD & PB1 domains
Occurring in:
  1. Protein kinase C iota type
The deposited structure of PDB entry 1vd2 contains 1 copy of SCOP domain 64225 (PB1 domain) in Protein kinase C iota type. Showing 1 copy in chain A.