Function and Biology

Crystal structure of an aig2-like protein (a2ld1, ggact, mgc7867) from mus musculus at 1.90 A resolution

Source organism: Mus musculus
Biochemical function: gamma-glutamylaminecyclotransferase activity
Biological process: modified amino acid catabolic process
Cellular component: not assigned

EC 4.3.2.8: Gamma-glutamylamine cyclotransferase

Reaction catalysed:
Epsilon-(gamma-L-glutamyl)-L-lysine = L-lysine + 5-oxo-L-proline
Systematic name:
Epsilon-(gamma-L-glutamyl)-L-lysine gamma-glutamyl cyclotransferase (5-oxo-L-proline producing)
Alternative Name(s):
  • GGACT

GO terms

Biochemical function:
Biological process:
Cellular component:
  • not assigned

Sequence family

Pfam Protein family (Pfam)
PF06094
Domain description: Gamma-glutamyl cyclotransferase, AIG2-like
Occurring in:
  1. Gamma-glutamylaminecyclotransferase
The deposited structure of PDB entry 1vkb contains 1 copy of Pfam domain PF06094 (Gamma-glutamyl cyclotransferase, AIG2-like) in Gamma-glutamylaminecyclotransferase. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR013024
Domain description: Gamma-glutamyl cyclotransferase-like
Occurring in:
  1. Gamma-glutamylaminecyclotransferase
IPR009288
Domain description: Gamma-glutamylcyclotransferase, AIG2-like domain
Occurring in:
  1. Gamma-glutamylaminecyclotransferase
IPR039126
Domain description: Gamma-glutamylaminecyclotransferase
Occurring in:
  1. Gamma-glutamylaminecyclotransferase
IPR036568
Domain description: Gamma-glutamyl cyclotransferase-like superfamily
Occurring in:
  1. Gamma-glutamylaminecyclotransferase

Structure domain

CATH CATH domain
3.10.490.10
Class: Alpha Beta
Architecture: Roll
Topology: Hypothetical upf0131 protein ytfp
Homology: Gamma-glutamyl cyclotransferase-like
Occurring in:
  1. Gamma-glutamylaminecyclotransferase
The deposited structure of PDB entry 1vkb contains 1 copy of CATH domain 3.10.490.10 (Hypothetical upf0131 protein ytfp) in Gamma-glutamylaminecyclotransferase. Showing 1 copy in chain A.
SCOP SCOP annotation
110858
Class: Alpha and beta proteins (a+b)
Fold: Gamma-glutamyl cyclotransferase-like
Superfamily: Gamma-glutamyl cyclotransferase-like
Occurring in:
  1. Gamma-glutamylaminecyclotransferase
The deposited structure of PDB entry 1vkb contains 1 copy of SCOP domain 110858 (Gamma-glutamyl cyclotransferase-like) in Gamma-glutamylaminecyclotransferase. Showing 1 copy in chain A.