› 1vsg

X-ray diffraction
2.9Å resolution

2.9 ANGSTROMS RESOLUTION STRUCTURE OF THE N-TERMINAL DOMAIN OF A VARIANT SURFACE GLYCOPROTEIN FROM TRYPANOSOMA BRUCEI

Released:
DOI: 10.2210/pdb1vsg/pdb
PDB entry 1vsg coloured by chain, front view.
PDB entry 1vsg coloured by chain, side view.
PDB entry 1vsg coloured by chain, top view.
Source organism: Trypanosoma brucei brucei
Primary publication:
2.9 A resolution structure of the N-terminal domain of a variant surface glycoprotein from Trypanosoma brucei.
Freymann D, Down J, Carrington M, Roditi I, Turner M, Wiley D
J Mol Biol 216 141-60 (1990)
PMID: 2231728

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domain:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-150700 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (3 distinct):
Variant surface glycoprotein MITAT 1.2 Chains: A, B
Molecule details ›
Chains: A, B
Length: 364 amino acids
Theoretical weight: 38.84 KDa
Source organism: Trypanosoma brucei brucei
Expression system: Not provided
UniProt:
  • Canonical: P26332 (Residues: 27-390; Coverage: 81%)
Sequence domains: Trypanosome variant surface glycoprotein (A-type)
Structure domains:

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA
Carbohydrate polymer
Carbohydrate polymer : NEW Components: NAG, MAN
Carbohydrate polymer
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P212121
Unit cell:
a: 95.5Å b: 97.5Å c: 123.7Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.22 0.22 not available
Expression system: Not provided

Quick links

Citations

12 review citations

Principles of protein-protein interactions.
Jones et al. (1996)
11 more

15 mentions without citation

Masters of Disguise: Antigenic Variation and the VSG Coat in Trypanosoma brucei.
Mugnier et al. (2016)
14 more