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Structure of superoxide reductase bound to ferrocyanide and active site expansion upon X-ray induced photoreduction

Source organism: Desulfarculus baarsii
Biochemical function: superoxide reductase activity
Biological process: removal of superoxide radicals
Cellular component: not assigned

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EC 1.15.1.2: Superoxide reductase

Reaction catalysed:
Reduced rubredoxin + superoxide + 2 H(+) = oxidized rubredoxin + H(2)O(2)
Systematic name:
Rubredoxin:superoxide oxidoreductase
Alternative Name(s):
  • Desulfoferrodoxin
  • Neelaredoxin

GO terms

Sequence families

Pfam Protein families (Pfam)
PF01880
Domain description: Desulfoferrodoxin
Occurring in:
  1. Desulfoferrodoxin
The deposited structure of PDB entry 1vzg contains 2 copies of Pfam domain PF01880 (Desulfoferrodoxin) in Desulfoferrodoxin. Showing 1 copy in chain A.

PF06397
Domain description: Desulfoferrodoxin, N-terminal domain
Occurring in:
  1. Desulfoferrodoxin
The deposited structure of PDB entry 1vzg contains 2 copies of Pfam domain PF06397 (Desulfoferrodoxin, N-terminal domain) in Desulfoferrodoxin. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR004462
Domain description: Desulfoferrodoxin, N-terminal domain
Occurring in:
  1. Desulfoferrodoxin
IPR002742
Domain description: Desulfoferrodoxin, ferrous iron-binding domain
Occurring in:
  1. Desulfoferrodoxin
IPR036073
Domain description: Desulfoferrodoxin, ferrous iron-binding domain superfamily
Occurring in:
  1. Desulfoferrodoxin
IPR038094
Domain description: Desulfoferrodoxin, N-terminal domain superfamily
Occurring in:
  1. Desulfoferrodoxin
IPR004793
Domain description: Desulfoferrodoxin
Occurring in:
  1. Desulfoferrodoxin

Structure domains

CATH CATH domains
2.60.40.730
Class: Mainly Beta
Architecture: Sandwich
Topology: Immunoglobulin-like
Homology: SOR catalytic domain
Occurring in:
  1. Desulfoferrodoxin
The deposited structure of PDB entry 1vzg contains 2 copies of CATH domain 2.60.40.730 (Immunoglobulin-like) in Desulfoferrodoxin. Showing 1 copy in chain A.
2.20.28.100
Class: Mainly Beta
Architecture: Single Sheet
Topology: Rubrerythrin, domain 2
Homology: Desulphoferrodoxin, N-terminal domain
Occurring in:
  1. Desulfoferrodoxin
The deposited structure of PDB entry 1vzg contains 2 copies of CATH domain 2.20.28.100 (Rubrerythrin, domain 2) in Desulfoferrodoxin. Showing 1 copy in chain A.
SCOP SCOP annotations
49368
Class: All beta proteins
Fold: Immunoglobulin-like beta-sandwich
Superfamily: Superoxide reductase-like
Occurring in:
  1. Desulfoferrodoxin
The deposited structure of PDB entry 1vzg contains 2 copies of SCOP domain 49368 (Superoxide reductase-like) in Desulfoferrodoxin. Showing 1 copy in chain A.
57813
Class: Small proteins
Fold: Rubredoxin-like
Superfamily: Rubredoxin-like
Occurring in:
  1. Desulfoferrodoxin
The deposited structure of PDB entry 1vzg contains 2 copies of SCOP domain 57813 (Desulforedoxin) in Desulfoferrodoxin. Showing 1 copy in chain A.

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