EC 7.1.2.2: H(+)-transporting two-sector ATPase
Reaction catalysed:
ATP + H(2)O + 4 H(+)(Side 1) = ADP + phosphate + 4 H(+)(Side 2)
Systematic name:
ATP phosphohydrolase (two-sector, H(+)-transporting)
Alternative Name(s):
- ATP synthase
- Bacterial Ca(2+)/Mg(2+) ATPase
- Chloroplast ATPase
- Coupling factors (F(o), F(1) and CF(1))
- F(0)F(1)-ATPase
- F(1)-ATPase
- F(o)F(1)-ATPase
- H(+)-transporting ATP synthase
- H(+)-transporting ATPase
- Mitochondrial ATPase
GO terms
Biochemical function:
Biological process:
Cellular component:
Sequence families
Protein families (Pfam)
InterPro annotations
IPR020003
Domain description:
ATPase, alpha/beta subunit, nucleotide-binding domain, active site
Occurring in:
Occurring in:
IPR000194
Domain description:
ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain
Occurring in:
Occurring in:
IPR004100
Domain description:
ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain
Occurring in:
Occurring in:
IPR036121
Domain description:
ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily
Occurring in:
Occurring in:
IPR038376
Domain description:
ATP synthase, alpha subunit, C-terminal domain superfamily
Occurring in:
Occurring in:
IPR033732
Domain description:
ATP synthase, F1 complex, alpha subunit nucleotide-binding domain
Occurring in:
Occurring in:
IPR023366
Domain description:
ATP synthase subunit alpha, N-terminal domain-like superfamily
Occurring in:
Occurring in:
Structure domains
CATH domains
3.40.50.300
Class:
Alpha Beta
Architecture:
3-Layer(aba) Sandwich
Topology:
Rossmann fold
Homology:
P-loop containing nucleotide triphosphate hydrolases
Occurring in:


1.10.1140.10
Class:
Mainly Alpha
Architecture:
Orthogonal Bundle
Topology:
Bovine Mitochondrial F1-ATPase, ATP Synthase Beta Chain; Chain D, domain3
Homology:
Bovine Mitochondrial F1-atpase; Atp Synthase Beta Chain; Chain D, domain 3
Occurring in:

2.40.10.170
Class:
Mainly Beta
Architecture:
Beta Barrel
Topology:
Thrombin, subunit H
Homology:
Thrombin, subunit H
Occurring in:

1.20.150.20
Class:
Mainly Alpha
Architecture:
Up-down Bundle
Topology:
Lysin
Homology:
ATP synthase alpha/beta chain, C-terminal domain
Occurring in:

2.40.30.20
Class:
Mainly Beta
Architecture:
Beta Barrel
Topology:
Elongation Factor Tu (Ef-tu); domain 3
Homology:
Elongation Factor Tu (Ef-tu); domain 3
Occurring in:

SCOP annotations
47918
Class:
All alpha proteins
Fold:
Left-handed superhelix
Superfamily:
C-terminal domain of alpha and beta subunits of F1 ATP synthase
Occurring in:


52670
Class:
Alpha and beta proteins (a/b)
Fold:
P-loop containing nucleoside triphosphate hydrolases
Superfamily:
P-loop containing nucleoside triphosphate hydrolases
Occurring in:


50616
Class:
All beta proteins
Fold:
Domain of alpha and beta subunits of F1 ATP synthase-like
Superfamily:
N-terminal domain of alpha and beta subunits of F1 ATP synthase
Occurring in:


52944
Class:
Alpha and beta proteins (a/b)
Fold:
Pyruvate kinase C-terminal domain-like
Superfamily:
ATP synthase (F1-ATPase), gamma subunit
Occurring in:
