Function and Biology

Structural properties of the B25Tyr-NMe-B26Phe insulin mutant.

Source organism: Homo sapiens
Biochemical function: hormone activity
Biological process: not assigned
Cellular component: extracellular region

GO terms

Biochemical function:
Biological process:
  • not assigned
Cellular component:

Sequence family

Pfam Protein family (Pfam)
PF00049
Domain description: Insulin/IGF/Relaxin family
Occurring in:
  1. Insulin B chain
The deposited structure of PDB entry 1w8p contains 6 copies of Pfam domain PF00049 (Insulin/IGF/Relaxin family) in Insulin B chain. Showing 1 copy in chain B.

InterPro InterPro annotations
IPR004825
Domain description: Insulin
Occurring in:
  1. Insulin B chain
IPR036438
Domain description: Insulin-like superfamily
Occurring in:
  1. Insulin A chain
  2. Insulin B chain
IPR016179
Domain description: Insulin-like
Occurring in:
  1. Insulin A chain
  2. Insulin B chain
IPR022353
Domain description: Insulin, conserved site
Occurring in:
  1. Insulin A chain