› 1wgm

Solution NMR

Solution structure of the U-box in human ubiquitin conjugation factor E4A

Released:
DOI: 10.2210/pdb1wgm/pdb
PDB entry 1wgm coloured by chain, ensemble of 20 models, front view.
PDB entry 1wgm coloured by chain, ensemble of 20 models, side view.
PDB entry 1wgm coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Entry authors: Saito K, Koshiba S, Inoue M, Kigawa T, Yokoyama S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Reaction catalysed: 
S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-171928 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ubiquitin conjugation factor E4 A Chain: A
Molecule details ›
Chain: A
Length: 98 amino acids
Theoretical weight: 10.92 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q14139 (Residues: 977-1061; Coverage: 8%)
Gene names: KIAA0126, UBE4A
Sequence domains: U-box domain
Structure domains: Zinc/RING finger domain, C3HC4 (zinc finger)

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Not provided

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