Function and Biology

Solution structure of the C2H2 zinc finger domain of the protein arginine N-methyltransferase 3 from Mus musculus

Source organism: Mus musculus
Biochemical function: not assigned
Biological process: not assigned
Cellular component: not assigned

EC 2.1.1.319: Type I protein arginine methyltransferase

Reaction catalysed:
(1a) S-adenosyl-L-methionine + [protein]-L-arginine = S-adenosyl-L-homocysteine + [protein]-N(omega)-methyl-L-arginine
Systematic name:
S-adenosyl-L-methionine:[protein]-L-arginine N-methyltransferase ([protein]-N(omega),N(omega)-dimethyl-L-arginine-forming)
Alternative Name(s):
  • CARM1 (gene name)
  • PRMT1 (gene name)
  • PRMT2 (gene name)
  • PRMT3 (gene name)
  • PRMT4 (gene name)
  • PRMT6 (gene name)
  • PRMT8 (gene name)
  • RMT1 (gene name)

GO terms

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence families

Pfam Protein families (Pfam)
PF21137
Domain description: Protein arginine N-methyltransferase 3, C2H2 zinc finger domain
Occurring in:
  1. Protein arginine N-methyltransferase 3
The deposited structure of PDB entry 1wir contains 1 copy of Pfam domain PF21137 (Protein arginine N-methyltransferase 3, C2H2 zinc finger domain) in Protein arginine N-methyltransferase 3. Showing 1 copy in chain A.

PF21336
Domain description: Protein arginine N-methyltransferase 3, C2H2 zinc finger
Occurring in:
  1. Protein arginine N-methyltransferase 3
The deposited structure of PDB entry 1wir contains 1 copy of Pfam domain PF21336 (Protein arginine N-methyltransferase 3, C2H2 zinc finger) in Protein arginine N-methyltransferase 3. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR040048
Domain description: Zinc finger protein 277
Occurring in:
  1. Protein arginine N-methyltransferase 3
IPR036236
Domain description: Zinc finger C2H2 superfamily
Occurring in:
  1. Protein arginine N-methyltransferase 3

Structure domain

SCOP SCOP annotation
118273
Class: Small proteins
Fold: beta-beta-alpha zinc fingers
Superfamily: beta-beta-alpha zinc fingers
Occurring in:
  1. Protein arginine N-methyltransferase 3
The deposited structure of PDB entry 1wir contains 1 copy of SCOP domain 118273 (variant C2H2 finger) in Protein arginine N-methyltransferase 3. Showing 1 copy in chain A.