› 1ww5

X-ray diffraction
2.2Å resolution

Agrocybe cylindracea galectin complexed with 3'-sulfonyl lactose

Released:
DOI: 10.2210/pdb1ww5/pdb
PDB entry 1ww5 coloured by chain, front view.
PDB entry 1ww5 coloured by chain, side view.
PDB entry 1ww5 coloured by chain, top view.
Source organism: Agrocybe cylindracea
Primary publication:
Structural basis of a fungal galectin from Agrocybe cylindracea for recognizing sialoconjugate.
Ban M, Yoon HJ, Demirkan E, Utsumi S, Mikami B, Yagi F
J Mol Biol 351 695-706 (2005)
PMID: 16051274

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-180509 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Anti-tumor lectin Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 160 amino acids
Theoretical weight: 16.91 KDa
Source organism: Agrocybe cylindracea
UniProt:
  • Canonical: Q6WY08 (Residues: 1-158; Coverage: 100%)
Sequence domains: Galactoside-binding lectin
Structure domains: Jelly Rolls

Ligands and Environments

Carbohydrate polymer : NEW Components: BGC, SGA
Carbohydrate polymer
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: MACSCIENCE
Spacegroup: P1
Unit cell:
a: 47.623Å b: 57.648Å c: 64.643Å
α: 89.96° β: 111.65° γ: 90.14°
R-values:
R R work R free
0.198 0.198 0.267

Quick links

Citations

6 review citations

Galectins as Molecular Targets for Therapeutic Intervention.
Dings et al. (2018)
5 more

1 mention without citation

Mushroom lectins: specificity, structure and bioactivity relevant to human disease.
Hassan et al. (2015)