› 1ww7

X-ray diffraction
1.9Å resolution

Agrocybe cylindracea galectin (Ligand-free)

Released:
DOI: 10.2210/pdb1ww7/pdb
PDB entry 1ww7 coloured by chain, front view.
PDB entry 1ww7 coloured by chain, side view.
PDB entry 1ww7 coloured by chain, top view.
Source organism: Agrocybe cylindracea
Primary publication:
Structural basis of a fungal galectin from Agrocybe cylindracea for recognizing sialoconjugate.
Ban M, Yoon HJ, Demirkan E, Utsumi S, Mikami B, Yagi F
J Mol Biol 351 695-706 (2005)
PMID: 16051274

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-180509 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Anti-tumor lectin Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 160 amino acids
Theoretical weight: 16.91 KDa
Source organism: Agrocybe cylindracea
UniProt:
  • Canonical: Q6WY08 (Residues: 1-158; Coverage: 100%)
Sequence domains: Galactoside-binding lectin
Structure domains: Jelly Rolls

Ligands and Environments

1 bound ligand:
Ligand SO4 4 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: MACSCIENCE
Spacegroup: P212121
Unit cell:
a: 57.071Å b: 96.307Å c: 121.656Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.203 0.203 0.252

Quick links

Citations

6 review citations

Galectins as Molecular Targets for Therapeutic Intervention.
Dings et al. (2018)
5 more

2 mentions without citation

Mushroom lectins: specificity, structure and bioactivity relevant to human disease.
Hassan et al. (2015)
1 more