› 1xpj

X-ray diffraction
2.3Å resolution

Crystal Structure of MCSG Target APC26283 from Vibrio cholerae

Released:
DOI: 10.2210/pdb1xpj/pdb
PDB entry 1xpj coloured by chain, front view.
PDB entry 1xpj coloured by chain, side view.
PDB entry 1xpj coloured by chain, top view.
Source organism: Vibrio cholerae
Entry authors: Brunzelle JS, Minasov G, Shuvalova L, Collart FR, Anderson WF, Midwest Center for Structural Genomics (MCSG)

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-192135 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Capsular polysaccharide biosynthesis protein Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 126 amino acids
Theoretical weight: 14.67 KDa
Source organism: Vibrio cholerae
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9KVB4 (Residues: 1-126; Coverage: 100%)
Gene name: VC_0232
Sequence domains: haloacid dehalogenase-like hydrolase
Structure domains: HAD superfamily/HAD-like

Ligands and Environments

2 bound ligands:
Ligand HG 4 x HG
Ligand TLA 4 x TLA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 5ID-B
Spacegroup: P21
Unit cell:
a: 77.729Å b: 52.888Å c: 72.215Å
α: 90° β: 90.2° γ: 90°
R-values:
R R work R free
0.203 0.201 0.253
Expression system: Escherichia coli BL21(DE3)

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