Function and Biology

Structural basis of prospero-DNA interaction; implications for transcription regulation in developing cells

Source organism: Drosophila melanogaster
Biochemical function: DNA binding
Biological process: regulation of DNA-templated transcription
Cellular component: not assigned

GO terms

Biochemical function:
Biological process:
Cellular component:
  • not assigned

Sequence family

Pfam Protein family (Pfam)
PF05044
Domain description: Homeo-prospero domain
Occurring in:
  1. Homeobox protein prospero
The deposited structure of PDB entry 1xpx contains 1 copy of Pfam domain PF05044 (Homeo-prospero domain) in Homeobox protein prospero. Showing 1 copy in chain C [auth A].

InterPro InterPro annotations
IPR023082
Domain description: Homeo-prospero domain
Occurring in:
  1. Homeobox protein prospero
IPR009057
Domain description: Homedomain-like superfamily
Occurring in:
  1. Homeobox protein prospero
IPR039350
Domain description: Prospero homeodomain family
Occurring in:
  1. Homeobox protein prospero
IPR037131
Domain description: Homeo-prospero domain superfamily
Occurring in:
  1. Homeobox protein prospero

Structure domain

CATH CATH domain
1.10.10.500
Class: Mainly Alpha
Architecture: Orthogonal Bundle
Topology: Arc Repressor Mutant, subunit A
Homology: Homeo-prospero domain
Occurring in:
  1. Homeobox protein prospero
The deposited structure of PDB entry 1xpx contains 1 copy of CATH domain 1.10.10.500 (Arc Repressor Mutant, subunit A) in Homeobox protein prospero. Showing 1 copy in chain C [auth A].
SCOP SCOP annotation
46690
Class: All alpha proteins
Fold: DNA/RNA-binding 3-helical bundle
Superfamily: Homeodomain-like
Occurring in:
  1. Homeobox protein prospero
The deposited structure of PDB entry 1xpx contains 1 copy of SCOP domain 46690 (Homeodomain) in Homeobox protein prospero. Showing 1 copy in chain C [auth A].