› 1ypt

X-ray diffraction
2.5Å resolution

CRYSTAL STRUCTURE OF YERSINIA PROTEIN TYROSINE PHOSPHATASE AT 2.5 ANGSTROMS AND THE COMPLEX WITH TUNGSTATE

Released:
DOI: 10.2210/pdb1ypt/pdb
PDB entry 1ypt coloured by chain, front view.
PDB entry 1ypt coloured by chain, side view.
PDB entry 1ypt coloured by chain, top view.
Source organism: Yersinia enterocolitica
Primary publication:
Crystal structure of Yersinia protein tyrosine phosphatase at 2.5 A and the complex with tungstate.
Stuckey JA, Schubert HL, Fauman EB, Zhang ZY, Dixon JE, Saper MA
Nature 370 571-5 (1994)
PMID: 8052312

Function and Biology Details

Reaction catalysed: 
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-147291 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tyrosine-protein phosphatase YopH Chains: A, B
Molecule details ›
Chains: A, B
Length: 305 amino acids
Theoretical weight: 33.42 KDa
Source organism: Yersinia enterocolitica
Expression system: Not provided
UniProt:
  • Canonical: P15273 (Residues: 164-468; Coverage: 65%)
Gene names: yop51, yopH
Sequence domains: Protein-tyrosine phosphatase
Structure domains: Protein tyrosine phosphatase superfamily

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P32
Unit cell:
a: 71.53Å b: 71.53Å c: 107.48Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.168 0.168 0.222
Expression system: Not provided

Quick links

Citations

57 review citations

The virulence plasmid of Yersinia, an antihost genome.
Cornelis et al. (1998)
56 more

18 mentions without citation

Overview of protein structural and functional folds.
Sun et al. (2004)
17 more