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Crystal structure of the macro-domain of human core histone variant macroH2A1.2

Source organism: Homo sapiens
Biochemical function: not assigned
Biological process: not assigned
Cellular component: not assigned

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GO terms

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence family

Pfam Protein family (Pfam)
PF01661
Domain description: Macro domain
Occurring in:
  1. Core histone macro-H2A.1
The deposited structure of PDB entry 1zr5 contains 2 copies of Pfam domain PF01661 (Macro domain) in Core histone macro-H2A.1. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR002589
Domain description: Macro domain
Occurring in:
  1. Core histone macro-H2A.1
IPR043472
Domain description: Macro domain-like
Occurring in:
  1. Core histone macro-H2A.1
IPR035796
Domain description: Core histone macro-H2A, macro domain
Occurring in:
  1. Core histone macro-H2A.1

Structure domain

CATH CATH domain
3.40.220.10
Class: Alpha Beta
Architecture: 3-Layer(aba) Sandwich
Topology: Leucine Aminopeptidase, subunit E; domain 1
Homology: Leucine Aminopeptidase, subunit E, domain 1
Occurring in:
  1. Core histone macro-H2A.1
The deposited structure of PDB entry 1zr5 contains 2 copies of CATH domain 3.40.220.10 (Leucine Aminopeptidase, subunit E; domain 1) in Core histone macro-H2A.1. Showing 1 copy in chain A.
SCOP SCOP annotation
89724
Class: Alpha and beta proteins (a/b)
Fold: Macro domain-like
Superfamily: Macro domain-like
Occurring in:
  1. Core histone macro-H2A.1
The deposited structure of PDB entry 1zr5 contains 2 copies of SCOP domain 89724 (Macro domain) in Core histone macro-H2A.1. Showing 1 copy in chain A.

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