› 2bjx

Solution NMR

PROTEIN DISULFIDE ISOMERASE

Released:
DOI: 10.2210/pdb2bjx/pdb
PDB entry 2bjx coloured by chain, ensemble of 24 models, front view.
PDB entry 2bjx coloured by chain, ensemble of 24 models, side view.
PDB entry 2bjx coloured by chain, ensemble of 24 models, top view.
Source organism: Homo sapiens
Primary publication:
The structure in solution of the b domain of protein disulfide isomerase.
Kemmink J, Dijkstra K, Mariani M, Scheek RM, Penka E, Nilges M, Darby NJ
J Biomol NMR 13 357-68 (1999)
PMID: 10383197

Function and Biology Details

Reaction catalysed: 
Catalyzes the rearrangement of -S-S- bonds in proteins
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-530015 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein disulfide-isomerase Chain: A
Molecule details ›
Chain: A
Length: 110 amino acids
Theoretical weight: 12.07 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P07237 (Residues: 136-245; Coverage: 22%)
Gene names: ERBA2L, P4HB, PDI, PDIA1, PO4DB
Sequence domains: Thioredoxin-like domain
Structure domains: Glutaredoxin

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: DISTANCE GEOMETRY AND SIMULATED ANNEALING
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

13 review citations

Proteins of the PDI family: unpredicted non-ER locations and functions.
Turano et al. (2002)
12 more

5 mentions without citation

Functions and mechanisms of protein disulfide isomerase family in cancer emergence.
Rahman et al. (2022)
4 more